Dermatology Unit, National Institute of Laser Enhanced Science, Cairo University, Cairo, Egypt.
Lasers Med Sci. 2011 Nov;26(6):825-9. doi: 10.1007/s10103-011-0982-2. Epub 2011 Aug 13.
Trichostasis spinulosa (TS) is a follicular disorder in which multiple hairs in a keratinous sheath project above the skin surface. Current treatments provide temporary relief and side effects are common. We report the successful treatment of TS in 20 patients using a short-pulsed 755-nm alexandrite laser. The 20 patients (skin types II-V) presented with TS lesions on the tip of their nose. All patients received a single treatment (one to three passes) with the laser with cold air cooling but without anaesthesia or analgesia. Treatment parameters were as follows: pulse duration 0.5 ms, fluence 15-17 J/cm(2), and spot size 5 mm. The entire procedure required less than 5 min to perform. The patients were followed up for 3 months for any adverse effects or recurrence. In all patients the lesions disappeared immediately after treatment with minimal or no pain. Erythema was minimal and lasted 5-20 min in all patients. Patients were very satisfied. The treated areas were still clear 4 to 5 weeks later, and a second treatment was not considered necessary. There were adverse effects other than the erythema and there was no recurrence within the follow-up period of 3 months. A single treatment with a short-pulsed 755-nm alexandrite laser appears to be a rapid, minimally painful, and effective treatment for TS in patients of skin types II to V.
毛发苔藓(TS)是一种毛囊角化性疾病,表现为角化性毳毛突出于皮肤表面。目前的治疗方法只能暂时缓解症状,且常伴有不良反应。我们报道了 20 例 TS 患者使用短脉冲 755nm 翠绿宝石激光治疗成功的案例。这 20 例患者(皮肤类型 II-V)均在鼻尖出现 TS 病变。所有患者均接受单次激光治疗(1-3 次),治疗时采用冷空气冷却,无需麻醉或镇痛。治疗参数如下:脉冲持续时间 0.5ms,能量密度 15-17J/cm2,光斑大小 5mm。整个过程耗时不到 5 分钟。患者在 3 个月内接受随访,观察有无不良反应或复发。所有患者治疗后病变立即消失,疼痛轻微或无疼痛。所有患者均有轻微红斑,持续 5-20min。患者非常满意。治疗后 4 至 5 周,治疗区域仍清晰,无需再次治疗。除红斑外,无其他不良反应,随访 3 个月内无复发。短脉冲 755nm 翠绿宝石激光单次治疗对于 II-V 型皮肤的 TS 患者是一种快速、轻微疼痛且有效的治疗方法。