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双相障碍、注意缺陷多动障碍青少年与非患者对照的睡眠初步研究。

A preliminary study of sleep in adolescents with bipolar disorder, ADHD, and non-patient controls.

机构信息

Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

出版信息

Bipolar Disord. 2011 Jun;13(4):425-32. doi: 10.1111/j.1399-5618.2011.00933.x.

Abstract

OBJECTIVES

To compare the sleep of adolescents with bipolar disorder (BD) to groups of adolescents with attention-deficit hyperactivity disorder-combined type (ADHD-C) and those without psychopathology.

METHODS

A sample of 13 adolescents diagnosed with BD who were not in the midst of a mood episode, 14 adolescents with ADHD-C, and 21 healthy controls, all between the ages of 11 and 17 years served as participants. They were psychiatrically evaluated using a structured diagnostic interview and completed four nights of in-home sleep monitoring using actigraphy and sleep diaries.

RESULTS

Sleep diary estimates of sleep indicated that participants with BD experienced more awakenings than their peers with ADHD, whereas actigraphic estimates revealed that participants with BD slept longer and with less wakefulness than their peers.

CONCLUSIONS

In between mood episodes, adolescents with BD experience their sleep as more fragmented than that of their peers but do not exhibit more disturbed sleep as estimated by actigraphy. The possible influence of psychotropic medication is an important consideration when assessing sleep in the context of BD.

摘要

目的

比较双相情感障碍(BD)青少年、注意缺陷多动障碍混合型(ADHD-C)青少年和无精神病理学青少年的睡眠。

方法

该研究纳入了 13 名未处于情绪发作期的 BD 青少年、14 名 ADHD-C 青少年和 21 名健康对照组青少年,年龄在 11 至 17 岁之间。他们通过结构化诊断访谈进行了精神病学评估,并使用活动记录仪和睡眠日记进行了 4 晚的家庭睡眠监测。

结果

睡眠日记估计的睡眠结果表明,BD 患者比 ADHD 患者经历更多的觉醒,而活动记录仪估计的睡眠结果表明,BD 患者比其同龄人睡得更长,且清醒时间更少。

结论

在情绪发作之间,BD 青少年的睡眠比同龄人更碎片化,但活动记录仪估计的睡眠并没有更紊乱。在评估 BD 背景下的睡眠时,精神药物的可能影响是一个重要的考虑因素。

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