Gladman D D, Urowitz M B, Keystone E C
Am J Med. 1979 Feb;66(2):210-5. doi: 10.1016/0002-9343(79)90529-1.
The significance of abnormal serologic tests in systemic lupus erythematosus (SLE) in the absence of active clinical disease is unclear. In this report we describe a group of 14 patients with SLE in whom a discordance between clinical and serologic features was apparent. These patients had persistently positive lupus erythematosus preparations and antinuclear antibody tests, low serum complement levels and high levels of DNA binding. Their lymphocyte response to concanavalin A (Con A) mitogen was suppressed. They have been asymptomatic and have remained untreated for a mean of four and a quarter years.
在无活动性临床疾病的情况下，系统性红斑狼疮（SLE）血清学检查异常的意义尚不清楚。在本报告中，我们描述了一组14例SLE患者，其临床和血清学特征之间存在明显不一致。这些患者的红斑狼疮细胞检查和抗核抗体试验持续呈阳性，血清补体水平低，DNA结合水平高。他们对刀豆球蛋白A（Con A）促细胞分裂剂的淋巴细胞反应受到抑制。他们一直无症状，平均未接受治疗达四年零三个月。
