Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine University Hospital of Patras, Patras, Greece.
Eur Rev Med Pharmacol Sci. 2011 Aug;15(8):937-42.
Total laryngectomy is a radical surgery for advanced laryngeal cancer. In the present study we evaluate the influencing factors for long term quality of life of 92 laryngectomees.
92 patients who underwent laryngectomy for laryngeal cancer in the University Hospital of Patras, Greece were evaluated using a modified version of the EORTC-QOL-C30 questionnaire. The patients were distributed into 6 groups based on time elapsed between surgical treatment and completion of the questionnaire, ranging from 2 years for group 1 to 9-10 years for group 6.
The mean value of psychological status (p=0.01), smelling disorders (p=0.032), mood change (p=0.003) were statistically significant in regard to the patient's overall view of their life postsurgically. Coexisting illness (defined as diabetes, hypertension or prostate disease which required medication on daily basis or hospitalization more than two times a year) was also significantly affecting (p=0.021) the patient's oral communication skills.
Quality of life is affected by functional disabilities and the psychological state of the patients. No statistically significant improvement over time was noted in our series.
全喉切除术是治疗晚期喉癌的根治性手术。本研究评估了 92 例喉癌全喉切除患者长期生活质量的影响因素。
希腊帕特雷大学医院的 92 例喉癌患者接受了全喉切除术,并使用 EORTC-QOL-C30 问卷的改良版进行了评估。根据手术治疗和完成问卷之间的时间间隔,患者被分为 6 组,从第 1 组的 2 年到第 6 组的 9-10 年。
在术后总体生活质量方面,心理状态(p=0.01)、嗅觉障碍(p=0.032)和情绪变化(p=0.003)的平均值具有统计学意义。并存疾病(定义为需要每天服药或每年住院两次以上的糖尿病、高血压或前列腺疾病)也显著影响(p=0.021)患者的口腔沟通能力。
生活质量受到功能障碍和患者心理状态的影响。我们的研究结果没有显示出随时间的显著改善。