64 层多排螺旋 CT 诊断附件肿瘤的准确性。

Accuracy of 64-multidetector computed tomography in diagnosis of adnexal tumors.

机构信息

Department of Radiology, Imam Reza Hospital, Tabriz University (Medical Sciences), Tabriz, Eastern Azerbaijan, Iran.

出版信息

J Ovarian Res. 2011 Aug 17;4:15. doi: 10.1186/1757-2215-4-15.

DOI:10.1186/1757-2215-4-15

PMID:21846406

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3170630/

Abstract

BACKGROUND

Adnexal cancers are in fifth place among the tumors with the highest mortality in the female population. The aim of the present study was to evaluate the accuracy of Multi-detector computed tomography (MDCT) on a 64-multislice CT scanner in the detection and differentiation of adnexal masses stages.

METHODS

During the present prospective study, 95 women with a primary diagnosis of ovarian mass in base of clinical examination and ultrasonographic findings underwent preoperative evaluation by a 64-slice MDCT with a section thickness of 0.6 mm, 50% overlap and reconstructed images. Afterward, results of MDCT were compared with surgical and histopathological findings, and the sensitivity, specificity, positive and negative predictive value and accuracy were determined.

RESULTS

The mean age of patients was 48.63 ± 13.93 years. MDCT diagnosed 25 (26.3%) masses to be benign and 70 (73.7%) to be malignant (sensitivity, specificity, positive and negative predictive value and accuracy were 92.8%, 88.0%, 95.5%, 81.4% and 91.5% respectively). The sensitivity and specificity of MDCT in determining local extension was 72.2% and 93.4% respectively. And the sensitivity and specificity of MDCT in determining peritoneal seeding and liver extension was 81.8% and 93% respectively. Estimated stage was significantly agreed with the surgical (Cohen's Kappa (κ) = 0.891) and histopathological findings (κ = 0.858).

CONCLUSION

MDCT is a highly sensitive and specific diagnostic method in evaluation of adnexal masses and successfully stage the tumor in consistent with surgery and histopathology.

摘要

背景

附件区肿瘤是女性人群中死亡率最高的肿瘤之一，位居第五位。本研究旨在评估在 64 层多排螺旋 CT 扫描仪上进行多探测器 CT（MDCT）对附件肿块分期的检测和鉴别诊断的准确性。

方法

在本前瞻性研究中，95 名女性患者经临床检查和超声检查初步诊断为卵巢肿块，对其行术前 64 层 MDCT 检查，层厚 0.6mm，重叠 50%，重建图像。随后，将 MDCT 结果与手术和组织病理学结果进行比较，并确定其敏感性、特异性、阳性预测值、阴性预测值和准确性。

结果

患者的平均年龄为 48.63±13.93 岁。MDCT 诊断 25 个肿块为良性（26.3%），70 个肿块为恶性（敏感性、特异性、阳性预测值、阴性预测值和准确性分别为 92.8%、88.0%、95.5%、81.4%和 91.5%）。MDCT 确定局部扩散的敏感性和特异性分别为 72.2%和 93.4%。MDCT 确定腹膜种植和肝转移的敏感性和特异性分别为 81.8%和 93.0%。MDCT 分期与手术（Cohen's Kappa（κ）=0.891）和组织病理学结果（κ=0.858）具有显著一致性。