Malak Mohammed, Tawfeeq Tawfeeq, Holzer Hananel, Tulandi Togas
Department of Obstetrics and Gynecology, McGill University, Montreal QC.
J Obstet Gynaecol Can. 2011 Jun;33(6):617-619. doi: 10.1016/S1701-2163(16)34910-6.
To identify risk factors for ectopic pregnancy after in vitro fertilization treatment.
We conducted a study among women who conceived after IVF treatment and evaluated the possible risk factors for ectopic pregnancy. The parameters evaluated were demographics of the patients, cause of infertility, and risk factors for ectopic pregnancy, including tubal infertility and previous ectopic pregnancy.
Of 365 women, 18 women had an ectopic pregnancy and 347 others had an intrauterine pregnancy (control group). The incidence of IVF ectopic pregnancy was 4.9%. The mean age was 34.2 ± 1.4 years in the ectopic group and 34.3 ± 0.2 years in the control group; mean BMI was 23.8 ± 1.0 in the ectopic group and 24.5 ± 0.9 in the control group. Previous ectopic pregnancy, previous IVF ectopic pregnancy, or smoking did not affect the occurrence of ectopic pregnancy in this population. Logistic regression analysis demonstrated that tubal factor infertility and previous surgery for endometriosis were risk factors for IVF ectopic pregnancy.
Tubal factor infertility and previous surgery for endometriosis appear to be risk factors for ectopic pregnancy after IVF treatment. Other factors that usually contribute to spontaneous ectopic pregnancy, including previous ectopic pregnancy, pelvic infection, and smoking, were not risk factors for IVF ectopic pregnancy in our study.
确定体外受精治疗后异位妊娠的危险因素。
我们对接受体外受精治疗后受孕的女性进行了一项研究，并评估了异位妊娠的可能危险因素。评估的参数包括患者的人口统计学特征、不孕原因以及异位妊娠的危险因素，包括输卵管性不孕和既往异位妊娠史。
在365名女性中，18名发生了异位妊娠，其他347名发生了宫内妊娠（对照组）。体外受精异位妊娠的发生率为4.9%。异位妊娠组的平均年龄为34.2±1.4岁，对照组为34.3±0.2岁；异位妊娠组的平均体重指数为23.8±1.0，对照组为24.5±0.9。既往异位妊娠史、既往体外受精异位妊娠史或吸烟对该人群异位妊娠的发生没有影响。逻辑回归分析表明，输卵管因素不孕和既往子宫内膜异位症手术史是体外受精异位妊娠的危险因素。
输卵管因素不孕和既往子宫内膜异位症手术史似乎是体外受精治疗后异位妊娠的危险因素。在我们的研究中，其他通常导致自然发生异位妊娠的因素，包括既往异位妊娠史、盆腔感染和吸烟，并非体外受精异位妊娠的危险因素。
