缺血性室性心律失常的细胞机制。
Cellular mechanism for ischemic ventricular arrhythmias.
作者信息
Opie L H, Clusin W T
机构信息
Medical Research Council/University of Cape Town Ischemic Heart Disease Research Unit, University of Cape Town Medical School, South Africa.
出版信息
Annu Rev Med. 1990;41:231-8. doi: 10.1146/annurev.me.41.020190.001311.
Abstract
Two of the major ionic abnormalities found early in ischemia are (a) loss of potassium with an increase in the extracellular potassium ion concentration and (b) an increase in free cytosolic calcium. Both of these ionic abnormalities can powerfully predispose to the development of arrhythmias.
摘要
在缺血早期发现的两个主要离子异常是
(a) 钾离子丢失，细胞外钾离子浓度升高；(b) 游离胞质钙增加。这两种离子异常都极易引发心律失常。
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