Head & Emeritus Professor, W.H.O. Collaborating Centre in Psychopharmacology, Department of Psychiatry, K.E.M. Hospital, Parel, Bombay-400 012.
Indian J Psychiatry. 1983 Apr;25(2):107-9.
Aggression is psychological and social menace. The safety of the patient as well as other members of the society is jeopardised due to severe acts of aggression. Hence control of aggressive behaviour gets a priority over various other symptoms. Various treatment modalities have been tried to control the act of aggression. We carried out this study to find out antiaggressive effect of lithium carbonate. Twenty resistant patients of varied psychiatric diagnosis showing aggressive behaviour completed this six weeks outdoor trial. They were started on lithium after initial assessment and were called once a week for evaluation with their relatives for total period of six weeks. Their lithium dose w,s adjusted and they were assessed on an aggression scale. We found clinical improvement in seventy percent of our cases. Our conclusion was that lithium has a definite role in controlling aggression.
攻击行为是一种心理和社会威胁。由于严重的攻击行为,患者和社会其他成员的安全受到威胁。因此,控制攻击行为比控制其他各种症状更为重要。已经尝试了各种治疗方法来控制攻击行为。我们进行这项研究是为了发现碳酸锂的抗攻击作用。二十名具有不同精神诊断的耐药患者表现出攻击行为,完成了这项为期六周的户外试验。在初步评估后,他们开始服用碳酸锂,并在六周的时间内每周与他们的亲属一起进行一次评估。根据他们的锂剂量进行调整,并根据攻击量表对他们进行评估。我们发现我们的病例中有百分之七十有临床改善。我们的结论是,锂在控制攻击行为方面有明确的作用。