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抑郁中的自杀意念与生物胺。

Suicidal ideation and biogenic amines in depression.

机构信息

Asst. Professor, Department of Psychiatry, Madras Medical College and Institute of Mental Health, Madras-600 010.

出版信息

Indian J Psychiatry. 1983 Oct;25(4):286-92.

Abstract

This report is based on the study of 40 depressives in an attempt to explore the possible association between the suicidal ideas and the biogenic amines. The severity of suicidal ideas was measured on Hamilton Depressive Rating Scale and their amine metabolites were measured (MHFG, HVA and 5 HIAA) in urine and C.S.F. It was observed that the level of 5 HIAA, and Serotonin (5 HT) was more related to suicidal ideas and was inversely related. The probable associations between these are discussed.

摘要

本报告基于对 40 名抑郁症患者的研究,旨在探讨自杀意念与生物胺之间可能存在的关联。采用汉密尔顿抑郁评定量表(HamiltonDepressiveRatingScale)评估自杀意念的严重程度,检测尿液和脑脊液中的单胺代谢产物(MHFG、HVA 和 5-HIAA)。结果表明,5-HIAA 和血清素(5-HT)水平与自杀意念更为相关,且呈负相关。对这些关联进行了讨论。

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本文引用的文献

1
A rating scale for depression.一种抑郁症评定量表。
J Neurol Neurosurg Psychiatry. 1960 Feb;23(1):56-62. doi: 10.1136/jnnp.23.1.56.
2
The clinical and laboratory significance of serotonin and catechol amines in bananas.
N Engl J Med. 1959 Jul 2;261(1):23-6. doi: 10.1056/NEJM195907022610104.
4
5-Hydroxytryptamine in the hind-brain of depressive suicides.抑郁自杀者后脑内的5-羟色胺
Br J Psychiatry. 1967 Dec;113(505):1407-11. doi: 10.1192/bjp.113.505.1407.
7
Abnormalities of indoleamines in affective disorders.情感障碍中吲哚胺的异常。
Arch Gen Psychiatry. 1972 May;26(5):474-8. doi: 10.1001/archpsyc.1972.01750230084016.

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