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闭经和 BMI 是 LNG-IUD 用户满意度的独立决定因素:中欧地区的横断面研究。

Amenorrhea and BMI as independent determinants of patient satisfaction in LNG-IUD users: cross-sectional study in a Central European district.

机构信息

Hospital of Neunkirchen, Neunkirchen, Austria.

出版信息

Gynecol Endocrinol. 2012 Feb;28(2):119-24. doi: 10.3109/09513590.2011.588751. Epub 2011 Aug 17.

Abstract

OBJECTIVE

This study investigated the satisfaction of women carrying the LNG-IUD and determined influencing factors, especially considering bleeding patterns and body mass index (BMI).

DESIGN

Cross sectional study.

SETTING

Gynecological offices in a Central European district.

PARTICIPANTS

1825 women aged between 18 and 60 years.

MEASUREMENT

While sitting in the waiting room, voluntary patients had to answer a questionnaire about their experiences with the levonorgestrel intrauterine device. One question was used to determine whether the women were current, former or not users of the intrauterine coil.

RESULTS

415 women who had some experiences with Mirena were found. Overall, 266 (65.7%) were "very satisfied," 83 (20.5%) "quite satisfied," 18 (4.4%) "moderate satisfied," 19 (4.7%) "less satisfied," and the same amount "really not satisfied" with the hormonal coil. Women with amenorrhea were more often "very satisfied" in general, than women with hypermenorrhea (178 (67.9%) vs. 3 (1.1%) p < 0.001). Concerning bleeding patterns, 295 (74.1%) were "very satisfied" and 23 (5.8%) "really not satisfied". 203 (91.0%) of all amenorrhoeic women were "very satisfied" with their bleeding patterns, but only 2 (9.5%) of all women with hypermenorrhea (p < 0.001 for α = 0.05). Amenorrhea particularly occurred in women who had a significantly lower body mass index (24.4 ± 4.4 kg/m(2) vs. 27.6 ± 6.5 kg/m(2) in women with hypermenorrhea, p = 0.018 for α = 0.05). After allocating women to the widely used BMI-categories (underweight, normal weight, overweight, obese class I and II) it was evident, that normally weighted women tend toward amenorrhea as well at the beginning of LNG-IUD use as well after 4-5 years of use. In contrast to this, overweighed and obese women tend more often to amenorrhea at the end of use, but not at the beginning (72.7% and 55.6% vs. 25.0% and 0%). Women with a lower BMI were more often "very satisfied" concerning bleeding patterns, but not concerning the general satisfaction.

CONCLUSION

Our study showed much evidence, that amenorrhea occurs more often in women with lower BMI contrary to women with a higher one-especially at the beginning of LNG- IUD use. Furthermore amenorrhea was mostly considered to be a positive menstrual change.

摘要

目的

本研究旨在调查携带 LNG-IUD 的女性的满意度,并确定影响因素,特别是考虑出血模式和体重指数(BMI)。

设计

横断面研究。

地点

中欧一个地区的妇科诊所。

参与者

年龄在 18 至 60 岁之间的 1825 名女性。

测量方法

在候诊室等待时,自愿的患者必须回答一份关于他们使用左炔诺孕酮宫内节育器经验的问卷。其中一个问题用于确定女性是宫内节育器的当前、以前或非使用者。

结果

发现了 415 名有一些 Mirena 经验的女性。总体而言,266 名(65.7%)“非常满意”,83 名(20.5%)“相当满意”,18 名(4.4%)“中度满意”,19 名(4.7%)“不太满意”,同样数量的女性(4.7%)对激素宫内节育器“非常不满意”。闭经的女性总体上比月经过多的女性更常“非常满意”(178 名(67.9%)比 3 名(1.1%),p <0.001)。关于出血模式,295 名(74.1%)“非常满意”,23 名(5.8%)“非常不满意”。所有闭经女性中,有 203 名(91.0%)“非常满意”她们的出血模式,但只有 2 名(9.5%)月经过多的女性(p <0.001,α=0.05)。闭经尤其发生在 BMI 明显较低的女性中(24.4 ± 4.4 kg/m2与月经过多的女性 27.6 ± 6.5 kg/m2相比,p = 0.018,α = 0.05)。将女性分配到广泛使用的 BMI 类别(体重不足、正常体重、超重、肥胖 I 级和 II 级)后,很明显,正常体重的女性在开始使用 LNG-IUD 时以及使用 4-5 年后也往往会出现闭经。相比之下,超重和肥胖的女性在使用结束时更常出现闭经,但在使用开始时则不然(72.7%和 55.6%比 25.0%和 0%)。BMI 较低的女性在出血模式方面更常“非常满意”,但在总体满意度方面则不然。

结论

我们的研究表明,闭经在 BMI 较低的女性中比 BMI 较高的女性更常见,尤其是在开始使用 LNG-IUD 时。此外,闭经大多被认为是一种积极的月经变化。

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