Lui K, Hellmann J, Soto G, Donoghue V, Daneman A
Department of Pediatrics, Hospital For Sick Children, Toronto, Canada.
J Paediatr Child Health. 1990 Feb;26(1):55-7. doi: 10.1111/j.1440-1754.1990.tb02380.x.
Using range-gated pulsed Doppler sonography, cerebral blood flow velocity (CBFV) waveforms from the anterior cerebral artery (ACA), middle cerebral artery (MCA) and circle of Willis artery (CW) were examined in a total of 34 newborn infants. We compared the pulsatility index (PI) from the three cerebral arteries sampled in 10 term and 10 preterm (29 +/- 2 weeks) newborn infants without a history of perinatal asphyxia or intracranial pathology. The Pl in the ACA ranged from 0.60 to 1.03. There were no significant differences in Pl between the three vessels by paired comparisons. The Pl of the MCA differed from that of the ACA by 0.00 +/- 0.05. The variation coefficient (CV) was 7%. For CW with ACA, the difference was 0.00 +/- 0.04 and CV was 6%. Both intra- and interexaminer variation in Pl measurements were studied in another 14 infants. The variation coefficients were 5-8% for all three cerebral arteries. We showed that CBFV waveform patterns were similar in regional cerebral arteries, with Pl being a consistent CBFV index. In normal cerebral circulation, the intervessel Pl differences were within observer variations. Deviation from this may suggest abnormal regional cerebral haemodynamics.
采用距离选通脉冲多普勒超声检查了34例新生儿大脑前动脉（ACA）、大脑中动脉（MCA）和 Willis 环动脉（CW）的脑血流速度（CBFV）波形。我们比较了10例足月儿和10例早产儿（29±2周）在无围产期窒息或颅内病变病史的情况下，从三条脑动脉采集的搏动指数（PI）。ACA的PI范围为0.60至1.03。配对比较显示，三条血管之间的PI无显著差异。MCA的PI与ACA的PI差异为0.00±0.05。变异系数（CV）为7%。对于CW与ACA，差异为0.00±0.04，CV为6%。在另外14例婴儿中研究了检查者内和检查者间PI测量的变异。三条脑动脉的变异系数均为5%-8%。我们发现，局部脑动脉的CBFV波形模式相似，PI是一个一致的CBFV指标。在正常脑循环中，血管间PI差异在观察者变异范围内。偏离此范围可能提示局部脑血流动力学异常。
