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印度楝更新:一种多功能阿育吠陀草药。

An update on Murraya koenigii spreng: a multifunctional Ayurvedic herb.

作者信息

Gupta Priyanka, Nahata Alok, Dixit Vinod K

机构信息

Department of Pharmaceutical Sciences, Dr. Hari Singh Gour University, Sagar 470003, India.

出版信息

Zhong Xi Yi Jie He Xue Bao. 2011 Aug;9(8):824-33.

PMID:21849142
Abstract

Murraya koenigii Spreng (Rutaceae), a medicinally important herb of Indian origin, has been used for centuries in the Ayurvedic system of medicine. Leaves, fruits, roots and bark of this plant are a rich source of carbazole alkaloids. These alkaloids have been reported for their various pharmacological activities such as antitumor, antiviral, anti-inflammatory, antidiarrhoeal, diuretic and antioxidant activities. Apart from these activities, the plant is reported to possess a wide spectrum of biological activities. Phytochemistry and pharmacology of this plant make a demand of an exhaustive review of its potential as a valuable therapeutic agent for the treatment and management of various ailments frequently affecting humans. The present review gives a detailed description of the phytochemical, pharmacological, clinical and pre-clinical works carried out on this medicinal herb and also throws light on its therapeutic potential.

摘要

印度楝(芸香科)是一种原产于印度的具有重要药用价值的草本植物,在阿育吠陀医学体系中已被使用了几个世纪。这种植物的叶子、果实、根和树皮富含咔唑生物碱。据报道,这些生物碱具有多种药理活性,如抗肿瘤、抗病毒、抗炎、止泻、利尿和抗氧化活性。除了这些活性外,该植物还具有广泛的生物活性。这种植物的植物化学和药理学需要对其作为治疗和管理经常影响人类的各种疾病的有价值治疗剂的潜力进行详尽综述。本综述详细描述了对这种药草进行的植物化学、药理学、临床和临床前研究,并阐明了其治疗潜力。

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An update on Murraya koenigii spreng: a multifunctional Ayurvedic herb.印度楝更新:一种多功能阿育吠陀草药。
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Evaluation of cytotoxic activity from Temurui ( [Linn.] Spreng) leaf extracts against HeLa cell line using MTT assay.
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Carbazole alkaloids from Murraya koenigii trigger apoptosis and autophagic flux inhibition in human oral squamous cell carcinoma cells.九里香中的咔唑生物碱可引发人口腔鳞状细胞癌细胞的凋亡并抑制自噬通量。
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