Rodriguez J, Claus D, Verellen G, Lyon G
Service de Neurologie Pédiatrique, Hôpital Universitaire St. Luc, UCL, Bruxelles, Belgium.
Dev Med Child Neurol. 1990 Apr;32(4):347-52. doi: 10.1111/j.1469-8749.1990.tb16947.x.
Ultrasound scans of a preterm neonate (27 weeks gestation) at seven weeks of age showed periventricular echo-free cavities, but these were no longer visible at 15 weeks, three weeks before the infant died. At autopsy, a linear glial scar, extending from the periventricular white-matter into the white axis of the parasagittal gyrus, was found in the area occupied by the periventricular cysts. The larger cavity was reduced to a slit-like excavation in the midst of glial tissue. Unsuspected focal infarcts in the cerebral cortex were also found. This observation demonstrates that transient echo-free cavities represent foci of cystic necrosis, which are subject to secondary collapse. In the authors' experience, the linear extension of periventricular leukomalacia (PVL) into the core of parasagittal gyri is a frequent feature of PVL, and one which cannot easily be accounted for by the usual explanations of border-zone ischaemic softening.
一名孕27周的早产儿在7周龄时的超声扫描显示脑室周围有无回声腔，但在婴儿死亡前三周即15周时这些腔已不再可见。尸检时，在脑室周围囊肿占据的区域发现一条线性胶质瘢痕，从脑室周围白质延伸至矢状旁回的白质轴。较大的腔在胶质组织中缩小为一条裂隙状凹陷。还发现了大脑皮质中未被怀疑的局灶性梗死。这一观察结果表明，短暂的无回声腔代表囊性坏死灶，会继发塌陷。根据作者的经验，脑室周围白质软化（PVL）向矢状旁回核心的线性延伸是PVL的常见特征，而通常关于边缘带缺血性软化的解释难以说明这一特征。
