2nd Department of Cardiology, Onassis Cardiac Surgery Center , Athens , Greece.
Biomarkers. 2011 Sep;16(6):457-65. doi: 10.3109/1354750X.2011.576431. Epub 2011 Aug 19.
A growing body of gender-related research in coronary artery disease is beginning to gradually elucidate differences between women and men. In patients presenting with acute coronary syndromes (ACS), these sex differences include varying risk factor profiles, accuracy of diagnostic testing, clinical presentations, treatment practices and outcomes. There is also a differential expression of cardiac biomarkers by sex, which remains unexplained. This paper reviews all the available information on the effect of gender on cardiac biomarkers by search of MEDLINE using the terms gender differences, biomarkers, ACS and revascularization procedures. A better understanding of the sex disparities in biomarkers along with all other clinical information is essential to optimal management and patient care in the future.
越来越多与性别相关的冠心病研究开始逐渐阐明女性和男性之间的差异。在出现急性冠状动脉综合征（ACS）的患者中，这些性别差异包括不同的危险因素谱、诊断检测的准确性、临床表现、治疗方法和结果。心脏生物标志物的表达也存在性别差异，但原因尚不清楚。本文通过搜索 MEDLINE 中的术语“性别差异”、“生物标志物”、“ACS”和“血运重建术”，综述了所有关于性别对心脏生物标志物影响的可用信息。更好地了解生物标志物中的性别差异以及所有其他临床信息，对于未来的最佳管理和患者护理至关重要。
