比较兔在七氟醚或异氟醚麻醉期间的动脉血气、动脉血氧饱和度和呼气末二氧化碳分压。
Comparison of the arterial blood gas, arterial oxyhaemoglobin saturation and end-tidal carbon dioxide tension during sevoflurane or isoflurane anaesthesia in rabbits.
机构信息
Department of Surgery, Faculty of Veterinary Medicine, Uludag University, 16190 Bursa, Turkey.
出版信息
Ir Vet J. 2006 May 1;59(5):278-81. doi: 10.1186/2046-0481-59-5-278.
The effects of sevoflurane or isoflurane on arterial blood gas, arterial oxyhaemoglobin saturation and end-tidal CO2 tension were monitored during induction and maintenance of anaesthesia in 10 premedicated New Zealand White (NZW) rabbits.For induction, the anaesthetic agents were delivered via a face-mask. After induction was completed, an endotracheal tube was introduced for maintenance of anaesthesia for a period of 90 minutes. Changes in heart rate, respiratory rate, arterial blood gas, arterial oxyhaemoglobin saturation, blood pH and end-tidal CO2 tension were recorded. Although sevoflurane and isoflurane produce similar cardiopulmonary effects in premedicated rabbits, sevoflurane provides a smoother and faster induction because of its lower blood/gas partition coefficient. Thus sevoflurane is probably a more suitable agent than isoflurane for mask induction and maintenance. Its lower blood solubility also makes sevoflurane more satisfactory than isoflurane for maintenance of anaesthesia because it allows the anaesthetist to change the depth of anaesthesia more rapidly.
在 10 只预先用药的新西兰白兔（NZW）的麻醉诱导和维持过程中，监测七氟醚或异氟醚对动脉血气、动脉血氧饱和度和呼气末二氧化碳分压的影响。诱导时，通过面罩给予麻醉剂。诱导完成后，插入气管内导管以维持麻醉 90 分钟。记录心率、呼吸频率、动脉血气、动脉血氧饱和度、血液 pH 值和呼气末二氧化碳分压的变化。尽管七氟醚和异氟醚在预先用药的兔子中产生相似的心肺效应，但由于其较低的血/气分配系数，七氟醚提供了更平稳、更快的诱导。因此，七氟醚可能比异氟醚更适合面罩诱导和维持。其较低的血液溶解度也使七氟醚比异氟醚更适合维持麻醉，因为它允许麻醉师更快速地改变麻醉深度。
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