Veterinary Science Centre, School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland.
Ir Vet J. 2008 Mar 1;61(3):163-8. doi: 10.1186/2046-0481-61-3-163.
The deposition of semen, bacteria and debris in the uterus of the mare after breeding normally induces a self-limiting endometritis. The resultant fluid and inflammatory products are cleared by 48 hours post cover. Mares that are susceptible to persistent post-breeding endometritis (PPBEM) have impaired uterine defence and clearance mechanisms, making them unable to resolve this inflammation within the normal time. This persists beyond 48 hours post-breeding and causes persistent fluid accumulation within the uterus. Mares with PPBEM have an increased rate of embryonic loss and a lower overall pregnancy rate than those without the condition. To enhance conception rates, mares at high risk need optimal breeding management as well as early diagnosis, followed by the most appropriate treatment. This article reviews the pathogenesis, diagnosis and treatment of PPBEM and the management of affected mares.
马配种后，精液、细菌和碎片在子宫内的沉积通常会引发自限性子宫内膜炎。在覆盖后 48 小时内，通过液体和炎症产物被清除。易感持续性配种后子宫内膜炎（PPBEM）的母马，其子宫防御和清除机制受损，使它们无法在正常时间内解决炎症。这一情况持续超过 48 小时，导致子宫内持续积液。与没有这种情况的母马相比，患有 PPBEM 的母马胚胎丢失率更高，总妊娠率更低。为了提高受孕率，高风险的母马需要最佳的配种管理以及早期诊断，然后是最合适的治疗。本文综述了 PPBEM 的发病机制、诊断和治疗，以及受影响母马的管理。
