de Visser Richard, Waites Louisa, Parikh Chandni, Lawrie Aaron
School of Psychology, University of Sussex, Falmer BN1 9QH, UK.
Sex Health. 2011 Sep;8(3):330-7. doi: 10.1071/SH10155.
Human papillomavirus (HPV) is the cause of almost all cases of cervical cancer. The current UK government immunisation program includes free routine HPV vaccination of girls aged 12-13, with a catch-up vaccination program for 13-18-year-old girls. The aim of this study was to identify correlates of intended and actual uptake of catch-up HPV vaccination.
An online questionnaire was completed by 591 young women aged 16-20.
Of the 350 women who had been offered catch-up HPV vaccination, 90.6% had accepted. In multivariate analyses, vaccine uptake was significantly correlated with subjective norms more supportive of HPV vaccination, and greater uptake of other childhood vaccinations (χ²(3))=39.34, P<0.01; 91.1% correctly classified; Nagelkerke pseudo-r²=0.23). Among the 241 women aged 16-20 who had not been offered HPV vaccination, the average intention was 3.70 on a five-point scale. Multivariate analyses revealed four significant independent predictors of stronger intentions to accept vaccination: subjective norms more supportive of HPV vaccination, greater worry about sexually transmissible infections, greater support for young people's sexual health services and greater support for childhood vaccination (F((4,236))=18.67, P<0.01; adjusted r²=0.23). Young women rated television advertisements, educational programs and television soaps as the most effective ways to encourage uptake of HPV vaccination.
Uptake of HPV vaccination may be increased if interventions use appropriate media to promote social norms supportive of HPV vaccination.
人乳头瘤病毒（HPV）几乎是所有宫颈癌病例的病因。英国现行政府免疫计划包括为12至13岁女孩提供免费的常规HPV疫苗接种，以及为13至18岁女孩提供补种疫苗计划。本研究的目的是确定补种HPV疫苗接种意愿及实际接种情况的相关因素。
591名16至20岁的年轻女性完成了一份在线问卷。
在350名获得补种HPV疫苗接种机会的女性中，90.6%接受了接种。在多变量分析中，疫苗接种与更支持HPV疫苗接种的主观规范以及更多接种其他儿童疫苗显著相关（χ²(3)=39.34，P<0.01；91.1%正确分类；Nagelkerke伪r²=0.23）。在241名未获得HPV疫苗接种机会的16至20岁女性中，在五分制量表上的平均意愿为3.70。多变量分析显示，有四个显著的独立预测因素表明接受疫苗接种的意愿更强：更支持HPV疫苗接种的主观规范、对性传播感染的更大担忧、对年轻人性健康服务的更大支持以及对儿童疫苗接种的更大支持（F((4,236))=18.67，P<0.01；调整后r²=0.23）。年轻女性将电视广告、教育节目和电视肥皂剧评为鼓励接种HPV疫苗的最有效方式。
如果干预措施使用适当的媒体来促进支持HPV疫苗接种的社会规范，HPV疫苗接种率可能会提高。
