Department of Chemical, Materials and Biomolecular Engineering, Storrs, CT 06269-3222, USA.
Biosens Bioelectron. 2011 Oct 15;28(1):393-8. doi: 10.1016/j.bios.2011.07.054. Epub 2011 Jul 28.
A novel amperometric nonenzymatic glucose sensor based on Au-doped NiO nanobelts has been successfully fabricated and applied to nonenzymatic glucose detection. Its electrochemical behavior towards the oxidation of glucose was compared with NiO nanofibers and Au microparticles prepared with a similar procedure. The NiO-Au hybrid nanobelts modified electrode displays greatly enhanced electrocatalytic activity towards glucose oxidation, revealing a synergistic effect between the matrix NiO and the doped Au. The as-prepared NiO-Au nanobelts based glucose sensor displays significantly lower onset potential, lower detection limit, higher sensitivity, and wider linear range than that of pristine NiO nanofibers modified electrode. Moreover, Au nanoparticles distributed in NiO nanofibers enabled amperometric glucose detection with insignificant interference from ascorbic acid and uric acid. These results indicate that the NiO-Au hybrid nanobelt is a promising candidate in the development of highly sensitive and selective nonenzymatic glucose sensors.
一种基于掺金氧化镍纳米带的新型电流型非酶葡萄糖传感器已被成功制备，并应用于非酶葡萄糖检测。其对葡萄糖氧化的电化学行为与采用类似方法制备的氧化镍纳米纤维和金纳米颗粒进行了比较。NiO-Au 杂化纳米带修饰电极对葡萄糖氧化具有显著增强的电催化活性，表明基质 NiO 和掺杂的 Au 之间存在协同效应。与原始 NiO 纳米纤维修饰电极相比，所制备的 NiO-Au 纳米带葡萄糖传感器具有更低的起始电位、更低的检测限、更高的灵敏度和更宽的线性范围。此外，分布在 NiO 纳米纤维中的金纳米颗粒使得安培葡萄糖检测不受抗坏血酸和尿酸的显著干扰。这些结果表明，NiO-Au 杂化纳米带是开发高灵敏度和选择性非酶葡萄糖传感器的有前途的候选材料。
