School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China.
School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China.
Talanta. 2018 Jul 1;184:136-142. doi: 10.1016/j.talanta.2018.02.057. Epub 2018 Feb 15.
A nonenzymatic glucose electrochemical sensor was constructed based on Au nanoparticles (AuNPs) decorated Ni metal-organic-framework (MOF)/Ni/NiO nanocomposite. Ni-MOF/Ni/NiO nanocomposite was synthesized by one-step calcination of Ni-MOF. Then AuNPs were loaded onto the Ni-based nanocomposites' surface through electrostatic adsorption. Through characterization by transmission electron microscopy (TEM), high resolution TEM (HRTEM) and energy disperse spectroscopy (EDS) mapping, it is found that the AuNPs were well distributed on the surface of Ni-based nanocomposite. Cyclic voltammetric (CV) study showed the electrocatalytic activity of Au-Ni nanocomposite was highly improved after loading AuNPs onto it. Amperometric study demonstrated that the Au-Ni nanocomposites modified glassy carbon electrode (GCE) exhibited a high sensitivity of 2133.5 mA M cm and a wide linear range (0.4-900 μM) toward the oxidation of glucose with a detection limit as low as 0.1 μM. Moreover, the reproducibility, selectivity and stability of the sensor all exhibited outstanding performance. We applied the as-fabricated high performance sensor to measure the glucose levels in human serum and obtained satisfactory results. It is believed that AuNPs decorated Ni MOF/Ni/NiO nanocomposite provides a new platform for developing highly performance electrochemical sensors in practical applications.
基于金纳米粒子（AuNPs）修饰的 Ni 金属有机骨架（MOF）/Ni/NiO 纳米复合材料构建了一种非酶葡萄糖电化学传感器。Ni-MOF/Ni/NiO 纳米复合材料通过一步煅烧 Ni-MOF 合成。然后通过静电吸附将 AuNPs 负载到 Ni 基纳米复合材料的表面上。通过透射电子显微镜（TEM）、高分辨率 TEM（HRTEM）和能谱（EDS）映射的表征，发现 AuNPs 均匀分布在 Ni 基纳米复合材料的表面上。循环伏安法（CV）研究表明，负载 AuNPs 后，Au-Ni 纳米复合材料的电催化活性得到了显著提高。安培研究表明，Au-Ni 纳米复合材料修饰的玻碳电极（GCE）对葡萄糖的氧化具有高灵敏度，为 2133.5 mA M cm，线性范围宽（0.4-900 μM），检测限低至 0.1 μM。此外，传感器的重现性、选择性和稳定性均表现出优异的性能。我们将所制备的高性能传感器应用于测量人血清中的葡萄糖水平，获得了令人满意的结果。相信 AuNPs 修饰的 Ni MOF/Ni/NiO 纳米复合材料为开发实际应用中高性能电化学传感器提供了新的平台。
