Department of Psychiatry, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Psychiatry Investig. 2011 Jun;8(2):102-6. doi: 10.4306/pi.2011.8.2.102. Epub 2011 Apr 8.
Panic disorder (PD) is frequently comorbid with insomnia, which could exacerbate panic symptoms and contribute to PD relapse. Research has suggested that characteristics are implicated in both PD and insomnia. However, there are no reports examining whether temperament and character affect insomnia in PD. Thus, we examined the relationship between insomnia and personality characteristics in PD patients.
Participants were 101 patients, recruited from 6 university hospitals in Korea, who met the DSM-IV-TR criteria for PD. We assessed sleep outcomes using the sleep items of 17-item Hamilton Depression Rating Scale (HAMD-17)(item 4=onset latency, item 5=middle awakening, and item 6=early awakening) and used the Cloninger's Temperament and Character Inventory-Revised-Short to assess personality characteristics. To examine the relationship between personality and insomnia, we used analysis of variance with age, sex, and severity of depression (total HAMD scores minus sum of the three sleep items) as the covariates.
There were no statistical differences (p>0.1) in demographic and clinical data between patients with and without insomnia. Initial insomnia (delayed sleep onset) correlated to a high score on the temperamental dimension of novelty seeking 3 (NS3)(F(1,96)=6.93, p=0.03). There were no statistical differences (p>0.1) in NS3 between patients with and without middle or terminal insomnia.
The present study suggests that higher NS3 is related to the development of initial insomnia in PD and that temperament and character should be considered when assessing sleep problems in PD patients.
惊恐障碍(PD)常与失眠共病,这可能会加重惊恐症状并导致 PD 复发。研究表明,特征与 PD 和失眠都有关。然而,目前尚无研究检查气质和性格是否会影响 PD 患者的失眠。因此,我们研究了 PD 患者中失眠与人格特征之间的关系。
参与者为 101 名来自韩国 6 所大学附属医院的符合 DSM-IV-TR PD 标准的患者。我们使用 17 项汉密尔顿抑郁评定量表(HAMD-17)的睡眠项目(项目 4=潜伏期,项目 5=中段觉醒,项目 6=早醒)评估睡眠结果,并使用 Cloninger 的气质和性格修订版短表评估人格特征。为了研究人格与失眠之间的关系,我们使用方差分析,以年龄、性别和抑郁严重程度(总 HAMD 评分减去三个睡眠项目的总和)为协变量。
失眠患者和无失眠患者在人口统计学和临床数据方面无统计学差异(p>0.1)。起始性失眠(入睡延迟)与气质维度的新奇寻求 3(NS3)高分相关(F(1,96)=6.93,p=0.03)。在 NS3 方面,有中段或终端失眠的患者与无失眠的患者之间无统计学差异(p>0.1)。
本研究表明,较高的 NS3 与 PD 中初始失眠的发生有关,在评估 PD 患者的睡眠问题时应考虑气质和性格。