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奥沙西泮:1989年的最新情况。

Oxazepam: update 1989.

作者信息

Ayd F J

机构信息

West Virginia University Medical Center, Charleston.

出版信息

Int Clin Psychopharmacol. 1990 Jan;5(1):1-15.

PMID:2185302
Abstract

Oxazepam is an anxiolytic with established clinical efficacy. Compared to other benzodiazepines it may offer advantages in some patient populations, such as the elderly. Oxazepam has not been associated with more or different risks than other benzodiazepines, and there is no evidence that physiological dependence occurs more frequently with oxazepam than other benzodiazepines. Available evidence suggests that oxazepam may be associated with a lower risk of seizure-induction than lorazepam and alprazolam, and that compared to diazepam, oxazepam may have lower abuse potential.

摘要

奥沙西泮是一种具有确切临床疗效的抗焦虑药。与其他苯二氮䓬类药物相比,它在某些患者群体(如老年人)中可能具有优势。奥沙西泮与其他苯二氮䓬类药物相比,并没有更多或不同的风险,也没有证据表明奥沙西泮比其他苯二氮䓬类药物更易发生生理依赖性。现有证据表明,与劳拉西泮和阿普唑仑相比,奥沙西泮诱发癫痫的风险可能更低,并且与地西泮相比,奥沙西泮的滥用可能性可能更低。

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