Nthumba Peter M
Plastic, Reconstructive and Hand Unit, AIC Kijabe Hospital, Kijabe 00220, Kenya.
J Med Case Rep. 2011 Aug 19;5:396. doi: 10.1186/1752-1947-5-396.
Ameloblastomas are rare lesions constituting 1% of all jaw tumors. Oral squamous cell carcinomas are common lesions; these constitute about 90% of all oral cancers. Concurrent tumors consisting of ameloblastoma and squamous cell carcinoma are extremely rare.
This case report describes a 35-year-old African man who presented with a large mandibular tumor with an orocutaneous fistula that was found to be an ameloblastoma on histopathological examination, with concurrent squamous cell carcinoma histology within the fistula. This presentation was consistent with a Marjolin's ulcer within an ameloblastoma.
Ameloblastomas and Marjolin's ulcers require different management strategies. Careful histopathological examination of surgical specimens is key to patient outcome, as treatment of these patients depends on an accurate diagnosis.
成釉细胞瘤是罕见病变，占所有颌骨肿瘤的1%。口腔鳞状细胞癌是常见病变，约占所有口腔癌的90%。由成釉细胞瘤和鳞状细胞癌组成的同时性肿瘤极为罕见。
本病例报告描述了一名35岁的非洲男性，其下颌出现一个伴有口腔皮肤瘘管的大肿瘤，经组织病理学检查发现为成釉细胞瘤，瘘管内同时存在鳞状细胞癌组织学表现。此表现符合成釉细胞瘤内的马乔林溃疡。
成釉细胞瘤和马乔林溃疡需要不同的治疗策略。对手术标本进行仔细的组织病理学检查是患者预后的关键，因为这些患者的治疗取决于准确的诊断。
