Ueta E, Yoneda K, Ohno A, Osaki T
Department of Oral Surgery, Kochi Medical School, Japan.
Int J Oral Maxillofac Surg. 1996 Oct;25(5):370-2. doi: 10.1016/s0901-5027(06)80033-0.
A 60-year-old woman, who had undergone curettage of a mandibular ameloblastoma about 20 years before, presented with recurrence of an ameloblastoma in the mandibular symphysis. This tumor was removed by a marginal resection. About 2 years later, the tumor recurred in the right mandibular ramus, and the patient underwent right mandibulectomy. About 6 months later, the tumor again recurred. Radical resection was performed, but invasion of the infraorbital region and cranial base was noted. An anterior craniotomy was then performed and the lesion removed. Histologically, proliferation of squamous cells associated with atypia was seen, and ameloblastic features were no longer observed. Metastasis to the lung was noted 1 year later.
一名60岁女性，约20年前曾接受下颌骨成釉细胞瘤刮除术，现下颌骨联合处成釉细胞瘤复发。该肿瘤通过边缘切除术切除。约2年后，肿瘤在右下颌支复发，患者接受了右下颌骨切除术。约6个月后，肿瘤再次复发。进行了根治性切除，但发现肿瘤侵犯了眶下区域和颅底。随后进行了前开颅手术并切除了病变。组织学检查可见伴有异型性的鳞状细胞增生，未再观察到成釉细胞特征。1年后发现肺转移。
