Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia 22908, USA.
Curr Biol. 2011 Aug 23;21(16):R638-40. doi: 10.1016/j.cub.2011.07.004.
There are many parallels between DNA replication in yeast and humans. Now, two recent studies extend this relationship by dissecting key conserved interactions necessary for initiation of the replisome.
酵母和人类的 DNA 复制之间存在许多相似之处。如今,两项最新研究通过剖析复制体起始所必需的关键保守相互作用,扩展了这种关系。