Division of Pulmonary, Allergy & Critical Care Medicine, University of Pittsburgh, 3459 Fifth Avenue, NW 628 MUH, Pittsburgh, PA 15213, United States.
Cytokine. 2011 Nov;56(2):435-41. doi: 10.1016/j.cyto.2011.07.021. Epub 2011 Aug 19.
Lipocalin 2 is a protein that has garnered a great deal of interest in multidisciplinary fields over the last two decades since its discovery. However, its exact function in metabolic processes remains to be completely characterized. More recently, it has come to light as a highly upregulated protein in the setting of injury and infection. This review focuses on lipocalin 2 regulation and its relationship to cytokine and endocrine signaling pathways.
脂联素 2 是一种蛋白质，自发现以来的过去二十年中，在多学科领域引起了极大的关注。然而，其在代谢过程中的确切功能仍有待完全阐明。最近，它作为一种在损伤和感染情况下高度上调的蛋白质而被发现。这篇综述重点介绍了脂联素 2 的调节及其与细胞因子和内分泌信号通路的关系。
