Department of Animal Sciences and Industry, College of Agriculture, Kansas State University, Manhattan, Kansas 66506, USA.
J Anim Sci. 2012 Jan;90(1):361-72. doi: 10.2527/jas.2011-3870. Epub 2011 Aug 19.
Four experiments were conducted to examine the effect of porcine circovirus type 2 (PCV2) vaccination on the response of growing and finishing pigs (PIC 337 × 1050) to increasing dietary Lys. Experiments 1 and 2 evaluated 38- to 65-kg gilts and barrows, respectively, and Exp. 3 and 4 evaluated 100- to 120-kg gilts and barrows, respectively. Gilts and barrows were housed separately in different barns. Treatments were allotted in a completely randomized design into 2 × 4 factorials with 2 PCV2 treatments (PCV2-vaccinated and nonvaccinated) and 4 standardized ileal digestible (SID) Lys:ME ratios (2.24, 2.61, 2.99, and 3.36 g/Mcal in Exp. 1 and 2 and 1.49, 1.86, 2.23, and 2.61 g/Mcal in Exp. 3 and 4) within each experiment. There were 5 pens per treatment. At the start of Exp. 1 and 2, there were more pigs per pen (P < 0.001) in vaccinated pens because vaccinated pigs had a greater survival rate than nonvaccinated pigs, and this increase was maintained throughout the experiments. Removal rate approached 30% in nonvaccinated barrows and more than 20% in nonvaccinated gilts. Observation suggested that the removals were largely due to PCV2-associated disease. No PCV2 vaccination × SID Lys:ME ratio interactions (P > 0.10) were observed in any of the 4 studies. In Exp. 1 and 2, PCV2-vaccinated pigs had increased (P < 0.001) ADG compared with nonvaccinated pigs. The growth response was primarily due to increases in ADFI, which suggests that vaccinated pigs have a greater Lys requirement (g/d) than nonvaccinated pigs. In Exp. 1, increasing the SID Lys:ME ratio increased (quadratic; P < 0.04) ADG and G:F, with pigs fed the 2.99 g/Mcal ratio having the greatest ADG and G:F. In Exp. 2, increasing the SID Lys:ME ratio improved (linear; P < 0.001) G:F. In Exp. 3, ADG and G:F increased (P < 0.05) in a quadratic manner as the SID Lys:ME ratio fed increased. In Exp. 4, increasing the SID Lys:ME ratio increased ADG (linear; P < 0.001) and G:F (quadratic; P = 0.03). Although PCV2 vaccination improved growth, the corresponding increase in ADFI did not increase the optimal SID Lys:ME ratio for growing and finishing barrows and gilts.
进行了四项实验，以检验猪圆环病毒 2 型 (PCV2) 疫苗接种对生长育肥猪（ PIC 337 × 1050）对增加日粮赖氨酸的反应的影响。实验 1 和 2 分别评估了 38-65 公斤的后备母猪和公猪，实验 3 和 4 分别评估了 100-120 公斤的后备母猪和公猪。后备母猪和公猪分别在不同的畜舍中饲养。处理采用完全随机设计，分为 2×4 因子，有 2 种 PCV2 处理（PCV2 疫苗接种和非疫苗接种）和 4 种标准化回肠可消化（SID）赖氨酸：ME 比（实验 1 和 2 中为 2.24、2.61、2.99 和 3.36 g/Mcal，实验 3 和 4 中为 1.49、1.86、2.23 和 2.61 g/Mcal）。每个实验中每个处理有 5 个栏。在实验 1 和 2 开始时，接种组每栏的猪更多（P<0.001），因为接种组的猪存活率高于非接种组，并且这种增加在整个实验中保持不变。淘汰率在非接种组公猪中接近 30%，在非接种组后备母猪中超过 20%。观察表明，淘汰主要是由于 PCV2 相关疾病引起的。在这 4 项研究中，均未观察到 PCV2 疫苗接种×SID 赖氨酸：ME 比的互作（P>0.10）。在实验 1 和 2 中，接种疫苗的猪与未接种疫苗的猪相比，ADG 增加（P<0.001）。生长反应主要是由于 ADFI 的增加，这表明接种疫苗的猪比未接种疫苗的猪对赖氨酸的需求（g/d）更高。在实验 1 中，增加 SID 赖氨酸：ME 比增加（二次；P<0.04）ADG 和 G:F，喂食 2.99 g/Mcal 比例的猪 ADG 和 G:F 最大。在实验 2 中，增加 SID 赖氨酸：ME 比改善（线性；P<0.001）G:F。在实验 3 中，随着所喂 SID 赖氨酸：ME 比的增加，ADG 和 G:F 呈二次增加（P<0.05）。在实验 4 中，随着 SID 赖氨酸：ME 比的增加，ADG（线性；P<0.001）和 G:F（二次；P=0.03）增加。尽管 PCV2 疫苗接种改善了生长，但相应的 ADFI 增加并没有增加生长育肥猪和后备母猪和公猪的最佳 SID 赖氨酸：ME 比。
