A mechanism emerges for the critical period hypothesis for estrogen treatment.
作者信息
Morrison John H
机构信息
Fishberg Department of Neuroscience and the Friedman Brain Institute, Mount Sinai School of Medicine, New York, NY 10029, USA.
出版信息
Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):14375-6. doi: 10.1073/pnas.1111672108. Epub 2011 Aug 19.
Abstract
摘要
相似文献
1
A mechanism emerges for the critical period hypothesis for estrogen treatment.雌激素治疗关键期假说的一种机制出现了。
Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):14375-6. doi: 10.1073/pnas.1111672108. Epub 2011 Aug 19.
2
C terminus of Hsc70-interacting protein (CHIP)-mediated degradation of hippocampal estrogen receptor-alpha and the critical period hypothesis of estrogen neuroprotection.CHIP 介导的海马雌激素受体-α降解与雌激素神经保护的关键期假说。
Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):E617-24. doi: 10.1073/pnas.1104391108. Epub 2011 Aug 1.
3
Estrogen receptor α and G-protein coupled receptor 30 mediate the neuroprotective effects of 17β-estradiol in novel murine hippocampal cell models.雌激素受体 α 和 G 蛋白偶联受体 30 介导 17β-雌二醇对新型鼠海马细胞模型的神经保护作用。
Neuroscience. 2010 Sep 29;170(1):54-66. doi: 10.1016/j.neuroscience.2010.06.076. Epub 2010 Jul 7.
4
Estradiol targets synaptic proteins to induce glutamatergic synapse formation in cultured hippocampal neurons: critical role of estrogen receptor-alpha.雌二醇作用于突触蛋白以诱导培养的海马神经元中谷氨酸能突触的形成：雌激素受体α的关键作用。
J Neurosci. 2007 Jun 27;27(26):6903-13. doi: 10.1523/JNEUROSCI.0909-07.2007.
5
Estrogens are neuroprotective factors for hypertensive encephalopathy.雌激素是高血压性脑病的神经保护因子。
J Steroid Biochem Mol Biol. 2015 Feb;146:15-25. doi: 10.1016/j.jsbmb.2014.04.001. Epub 2014 Apr 13.
6
Estrogen can act via estrogen receptor alpha and beta to protect hippocampal neurons against global ischemia-induced cell death.雌激素可通过雌激素受体α和β发挥作用，保护海马神经元免受全脑缺血诱导的细胞死亡。
Endocrinology. 2005 Jul;146(7):3070-9. doi: 10.1210/en.2004-1515. Epub 2005 Apr 7.
7
Differential mechanisms of neuroprotection by 17 beta-estradiol in apoptotic versus necrotic neurodegeneration.17β-雌二醇在凋亡性与坏死性神经退行性变中的神经保护差异机制。
J Neurosci. 2001 Apr 15;21(8):2600-9. doi: 10.1523/JNEUROSCI.21-08-02600.2001.
8
Estrogen receptor-mediated neuroprotection from oxidative stress requires activation of the mitogen-activated protein kinase pathway.雌激素受体介导的针对氧化应激的神经保护作用需要丝裂原活化蛋白激酶途径的激活。
Endocrinology. 2003 Jan;144(1):306-12. doi: 10.1210/en.2002-220698.
9
Chronic nicotine exposure inhibits 17beta-estradiol-mediated protection of the hippocampal CA1 region against cerebral ischemia in female rats.长期暴露于尼古丁会抑制17β-雌二醇对雌性大鼠海马CA1区的脑缺血保护作用。
Neurosci Lett. 2009 Jul 17;458(2):65-9. doi: 10.1016/j.neulet.2009.04.021. Epub 2009 Apr 14.
10
Neuroprotection in Parkinsonian-treated mice via estrogen receptor α activation requires G protein-coupled estrogen receptor 1.通过激活雌激素受体α对帕金森病治疗小鼠进行神经保护需要G蛋白偶联雌激素受体1。
Neuropharmacology. 2015 Aug;95:343-52. doi: 10.1016/j.neuropharm.2015.04.006. Epub 2015 Apr 17.
引用本文的文献
1
Current evidence and therapeutic implication of PANoptosis in cancer.目前关于 PANoptosis 在癌症中的证据和治疗意义。
Theranostics. 2024 Jan 1;14(2):640-661. doi: 10.7150/thno.91814. eCollection 2024.
2
Sex-specific risk of cardiovascular disease and cognitive decline: pregnancy and menopause.性别特异性心血管疾病和认知能力下降风险：妊娠和绝经。
Biol Sex Differ. 2013 Mar 28;4(1):6. doi: 10.1186/2042-6410-4-6.
3
A dominant negative ERβ splice variant determines the effectiveness of early or late estrogen therapy after ovariectomy in rats.一种显性负性 ERβ 剪接变异体决定了去卵巢大鼠在早期或晚期雌激素治疗后的有效性。
PLoS One. 2012;7(3):e33493. doi: 10.1371/journal.pone.0033493. Epub 2012 Mar 13.
本文引用的文献
1
C terminus of Hsc70-interacting protein (CHIP)-mediated degradation of hippocampal estrogen receptor-alpha and the critical period hypothesis of estrogen neuroprotection.CHIP 介导的海马雌激素受体-α降解与雌激素神经保护的关键期假说。
Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):E617-24. doi: 10.1073/pnas.1104391108. Epub 2011 Aug 1.
2
Interactive effects of age and estrogen on cortical neurons: implications for cognitive aging.年龄和雌激素对皮质神经元的交互作用：对认知衰老的影响。
Neuroscience. 2011 Sep 15;191:148-58. doi: 10.1016/j.neuroscience.2011.05.045. Epub 2011 Jun 2.
3
Oophorectomy, menopause, estrogen treatment, and cognitive aging: clinical evidence for a window of opportunity.卵巢切除术、绝经、雌激素治疗和认知衰老：机会之窗的临床证据。
Brain Res. 2011 Mar 16;1379:188-98. doi: 10.1016/j.brainres.2010.10.031. Epub 2010 Oct 18.
4
Synaptic estrogen receptor-alpha levels in prefrontal cortex in female rhesus monkeys and their correlation with cognitive performance.雌性恒河猴前额皮质中的突触雌激素受体-α水平及其与认知表现的相关性。
J Neurosci. 2010 Sep 22;30(38):12770-6. doi: 10.1523/JNEUROSCI.3192-10.2010.
5
Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation.雌激素通过雌激素受体α介导的对NADPH氧化酶激活的抑制作用减轻缺血性氧化损伤。
J Neurosci. 2009 Nov 4;29(44):13823-36. doi: 10.1523/JNEUROSCI.3574-09.2009.
6
Estrogen therapy: is time of initiation critical for neuroprotection?雌激素治疗：起始时间对神经保护至关重要吗？
Nat Rev Endocrinol. 2009 Nov;5(11):620-7. doi: 10.1038/nrendo.2009.193.
7
Frontiers proposal. National Institute on Aging "bench to bedside: estrogen as a case study".前沿研究提案。美国国立衰老研究所“从 bench 到 bedside：以雌激素为例的研究” （注：“bench to bedside”直译为“从实验室到临床应用”，这里意译为“从 bench 到 bedside”，“bench”指代基础研究阶段，“bedside”指代临床应用阶段 ）
Age (Dordr). 2009 Sep;31(3):199-210. doi: 10.1007/s11357-009-9087-2. Epub 2009 Mar 10.
8
Estrogens and age-related memory decline in rodents: what have we learned and where do we go from here?雌激素与啮齿动物年龄相关的记忆衰退：我们学到了什么，以及未来何去何从？
Horm Behav. 2009 Jan;55(1):2-23. doi: 10.1016/j.yhbeh.2008.08.015. Epub 2008 Sep 16.
9
The healthy cell bias of estrogen action: mitochondrial bioenergetics and neurological implications.雌激素作用的健康细胞偏向性：线粒体生物能量学及神经学意义
Trends Neurosci. 2008 Oct;31(10):529-37. doi: 10.1016/j.tins.2008.07.003. Epub 2008 Sep 4.
10
Uncovering the mechanisms of estrogen effects on hippocampal function.揭示雌激素对海马体功能影响的机制。
Front Neuroendocrinol. 2008 May;29(2):219-37. doi: 10.1016/j.yfrne.2007.08.006. Epub 2007 Oct 15.
Zotero 插件