Onakewhor J U, Olagbuji B N, Ande A B, Ezeanochie M C, Olokor O E, Okonofua F E
Materno-Foetal Unit, Department of Obstetrics and Gynaecology, University of Benin Teaching Hospital, Benin-City, Edo State, Nigeria.
Ghana Med J. 2011 Jun;45(2):54-9. doi: 10.4314/gmj.v45i2.68929.
To determine the causes and characteristics of maternal deaths in HIV-infected women.
A retrospective study of maternal deaths in a cohort of HIV-infected women.
A facility-based maternal death review using case records and mortality summaries.
Thirty seven maternal deaths which occurred in HIV-infected women were reviewed in a university teaching hospital in southern Nigeria over a 4-year period. Causes and circumstances surrounding each maternal death were identified.
One in every four maternal deaths occur in women with HIV infection. Majority (64.9%) of the women presented in advanced stage (WHO stage III/IV) of HIV syndrome while 86.5% had missed opportunities for antiretroviral programme. Pregnancy-related sepsis was the commonest cause of maternal death. Other common causes were death from tuberculosis and pneumonia.
HIV-related maternal death is emerging as a leading cause of pregnancy related death in Nigeria. There is need to scale-up preconception care and ensure comprehensive and sustainable prevention of mother -to-child transmission service for all pregnant women throughout Nigeria to reduce the burden of HIV/AIDS infection and minimize avoidable deaths from opportunistic infections.
确定感染艾滋病毒妇女孕产妇死亡的原因和特征。
对一组感染艾滋病毒妇女的孕产妇死亡情况进行回顾性研究。
基于医疗机构的孕产妇死亡审查,使用病例记录和死亡率摘要。
在尼日利亚南部一家大学教学医院,对4年期间发生在感染艾滋病毒妇女中的37例孕产妇死亡病例进行了审查。确定了每例孕产妇死亡的原因和相关情况。
每四例孕产妇死亡中就有一例发生在感染艾滋病毒的妇女中。大多数(64.9%)妇女处于艾滋病毒综合征晚期(世界卫生组织III/IV期),而86.5%的妇女错过了接受抗逆转录病毒治疗方案的机会。与妊娠相关的败血症是孕产妇死亡最常见的原因。其他常见原因是结核病和肺炎导致的死亡。
在尼日利亚,与艾滋病毒相关的孕产妇死亡正成为妊娠相关死亡的主要原因。有必要扩大孕前保健,并确保为尼日利亚所有孕妇提供全面和可持续的预防母婴传播服务,以减轻艾滋病毒/艾滋病感染负担,并尽量减少机会性感染导致的可避免死亡。