Centre for Health Services Research, School of Population Health, The University of Western Australia, 35 Stirling Highway, Crawley, Western Australia, Australia.
Obes Surg. 2012 Jan;22(1):97-104. doi: 10.1007/s11695-011-0493-z.
We compared percent excess body mass index loss (%EBMIL) and resolution of dyslipidaemia, hypertension, and type 2 diabetes mellitus in the 4 years following laparoscopic sleeve gastrectomy (LSG) between patients calibrated with a 40-French (40F) or a 50-French (50F) bougie.
We conducted a longitudinal retrospective descriptive study of routinely collected pre- and post-surgical data from 294 patients who underwent LSG at a single surgical centre (50F--n = 106, 40F--n = 185). Obesity measurements were taken prior to surgery and at regular intervals until 48 months post-surgery. Co-morbidity resolution was also assessed across the 48-month observation period. Multivariate regression modelling was used to control analyses for baseline obesity and sociodemographic variables.
At 48 months post-surgery mean (±SD) %EBMIL was 60.2 ± 27.6% and 45.4 ± 38.4% for those treated with the 40F and 50F bougie, respectively. After controlling for sociodemographic variables and baseline excess weight, mean %EBMIL was 15.5% greater with a 40F bougie compared with a 50F bougie at the end of follow-up. The likelihood of dyslipidaemia resolution within 48 months post-LSG was 19.0 times greater (p = 0.006), hypertension resolution 3.6 times greater (p = 0.005) and type 2 diabetes mellitus resolution 5.2 times greater (p = 0.034) by 4 years post-surgery in patients treated with the 40F bougie compared with a 50F bougie.
Improved obesity reduction and resolution of dyslipidaemia, hypertension and type 2 diabetes mellitus is experienced during the 4 years following surgery by patients treated with a 40F bougie compared with the 50F. These findings remain when controlling for potential confounding clinical and sociodemographic factors.
我们比较了使用 40F 或 50F 测径器校准的患者在腹腔镜袖状胃切除术（LSG）后 4 年内的超重指数损失百分比（%EBMIL）和血脂异常、高血压和 2 型糖尿病的缓解情况。
我们对一家外科中心的 294 例 LSG 患者的常规术前和术后数据进行了纵向回顾性描述性研究（50F-n=106，40F-n=185）。肥胖测量值在术前和术后定期进行，直到 48 个月。在 48 个月的观察期内还评估了合并症的缓解情况。使用多元回归模型控制分析基线肥胖和社会人口统计学变量。
在术后 48 个月时，40F 和 50F 测径器治疗的患者的平均（±SD）%EBMIL 分别为 60.2±27.6%和 45.4±38.4%。在校正社会人口统计学变量和基线超重后，40F 测径器治疗的患者的平均%EBMIL 在随访结束时比 50F 测径器治疗的患者高 15.5%。与 50F 测径器相比，40F 测径器治疗的患者在术后 48 个月内血脂异常缓解的可能性高 19.0 倍（p=0.006），高血压缓解的可能性高 3.6 倍（p=0.005），2 型糖尿病缓解的可能性高 5.2 倍（p=0.034）。
与 50F 测径器相比，使用 40F 测径器治疗的患者在术后 4 年内，肥胖减轻和血脂异常、高血压和 2 型糖尿病的缓解情况更好。在控制潜在的混杂临床和社会人口统计学因素后，这些发现仍然存在。
