四氧化锇，N，N，N'，N'-四甲基乙二胺。一种用于探测细胞中DNA结构的新探针。
Osmium tetroxide, N,N,N',N'-tetramethylethylendiamine. A new probe of DNA structure in the cell.
作者信息
Boublíková P, Palecek E
机构信息
Institute of Biophysics, Czechoslovak Academy of Sciences, Brno.
出版信息
FEBS Lett. 1990 Apr 24;263(2):281-4. doi: 10.1016/0014-5793(90)81393-3.
PMID:2185954
Abstract
It was shown that the complex of osmium tetroxide with N,N,N',N'-tetramethylethylendiamine can be applied as a probe of DNA structure in the cell. This probe site-specifically recognized structural distortions at the B-Z junctions in plasmids pRW751 and pPK1 (containing (dC-dG)n segments) in E. coli cells.
摘要
已表明，四氧化锇与N,N,N',N'-四甲基乙二胺的复合物可作为细胞中DNA结构的探针。该探针能位点特异性地识别大肠杆菌细胞中质粒pRW751和pPK1（含有(dC-dG)n片段）中B-Z连接处的结构畸变。
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