Ikeme A C, Ezegwui H U, Ikeako L C, Agbata I, Agbata E
Department of Obstetrics and Gynaecology,Anambra State-University Teaching Hospital, Amaku, Awka, Nigeria.
Niger J Clin Pract. 2011 Apr-Jun;14(2):176-80. doi: 10.4103/1119-3077.84010.
Chlamydia infections in women cause pelvic inflammatory disease, which often results in devastating consequences of infertility, ectopic pregnancy, or chronic pelvic pain. The infection is largely asymptomatic.
To determine the seroprevalence of Chlamydia trachomatis in Enugu, South Eastern Nigeria.
A population-based prospective study comprising female residents of Enugu, South Eastern Nigeria. Indirect solid phase enzyme immunoassay of Chlamydia antibodies was done using ImmunoComb C0. Trachomatis IgG Kit (Orgenics).
The population comprised 136 female undergraduate students and 150 non-student women. The overall prevalence of C. trachomatis in the population studied was 29.4%. The percentage of subjects who admitted to be having multiple sexual partners was higher among the student population (71.2%) compared to those from the non-student population (28.8%). The highest percentage of seroprevalence was 28 (33.3%) in the age group of 20-24 years for the student population and 18 (21.4%) in the age group of 25-29 years for the non-student population. The highest seroprevalence of C. trachomatis antibodies (69.0%) in both populations was observed in females without any history of infection. Females that had pelvic inflammatory disease, sexually transmitted infection, and secondary infertility assayed for C. trachomatis had seroprevalence levels of 19%, 9.5%, and 2.4%, respectively. There was a positive correlation between positive Chlamydia assay and the type of subject population (student or non-student) with r2 value of 1.55 at P < 0.01.
C. trachomatis infection is largely underdiagnosed and remains a silent disease in the apparently healthy population of Enugu, South eastern Nigeria.
女性衣原体感染会引发盆腔炎，常导致不孕、宫外孕或慢性盆腔疼痛等严重后果。该感染大多无症状。
确定尼日利亚东南部埃努古地区沙眼衣原体的血清流行率。
一项基于人群的前瞻性研究，研究对象为尼日利亚东南部埃努古地区的女性居民。使用ImmunoComb C0.沙眼衣原体IgG试剂盒（奥津尼克斯公司）进行衣原体抗体的间接固相酶免疫测定。
研究人群包括136名本科女学生和150名非学生女性。在所研究的人群中，沙眼衣原体的总体流行率为29.4%。承认有多个性伴侣的学生人群比例（71.2%）高于非学生人群（28.8%）。学生人群中20 - 24岁年龄组的血清流行率最高，为28例（33.3%）；非学生人群中25 - 29岁年龄组的血清流行率最高，为18例（21.4%）。在无任何感染史的女性中，观察到沙眼衣原体抗体的最高血清流行率（69.0%）。患有盆腔炎、性传播感染和继发性不孕的女性检测沙眼衣原体的血清流行率分别为19%、9.5%和2.4%。衣原体检测阳性与研究对象类型（学生或非学生）之间存在正相关，r2值为1.55，P < 0.01。
在尼日利亚东南部埃努古地区看似健康的人群中，沙眼衣原体感染大多未被诊断出来，仍然是一种隐匿性疾病。
