Neves Fábio Fernandes, Faiolla Rivian Christina Lopes, Napoli Emília Maria Guimarães de, Lima Geovana Momo Nogueira de, Muniz Renata Zomer de Albernaz, Pazin-Filho Antônio
Departamento de Medicina, Universidade Federal de São Carlos, São Carlos, SP.
Rev Soc Bras Med Trop. 2011 Jul-Aug;44(4):481-5. doi: 10.1590/s0037-86822011000400016.
Tetanus remains a major health problem in developing countries. In Brazil, despite technological advances, no significant decrease in the lethality rate of tetanus have been documented in recent years. Clinical and epidemiological data from patients who were treated in Ribeirão Preto in the state of São Paulo, Brazil in the last two decades were analyzed in this case series.
Retrospective data regarding the demographics, clinical presentations and prognoses of patients admitted with clinical suspicion of tetanus to a tertiary referral university hospital from 1990 to 2009 were identified. The tetanus diagnosis was defined according to the Brazilian Ministry of Health criteria.
Eleven cases out of 23 patients with suspected tetanus were included in this study (47.8% of positive cases). The Tetanus Severity Score ranged from 0 to 8 points. There were no deaths, but two (18.2%) patients had permanent neurological deficits. The median length of hospital stay was 17 days (6-98 days). The absence of deaths can be explained by early clinical diagnosis and prompt treatment.
Ribeirão Preto is an area in which tetanus is not a severe public health problem.
破伤风在发展中国家仍然是一个重大的健康问题。在巴西，尽管有技术进步，但近年来破伤风致死率并未有显著下降。在此病例系列中，分析了过去二十年在巴西圣保罗州里贝朗普雷图接受治疗的患者的临床和流行病学数据。
确定了1990年至2009年因临床怀疑破伤风而入住一家三级转诊大学医院的患者的人口统计学、临床表现和预后的回顾性数据。破伤风诊断根据巴西卫生部标准确定。
本研究纳入了23例疑似破伤风患者中的11例（阳性病例的47.8%）。破伤风严重程度评分范围为0至8分。无死亡病例，但有两名（18.2%）患者有永久性神经功能缺损。中位住院时间为17天（6 - 98天）。无死亡病例可归因于早期临床诊断和及时治疗。
里贝朗普雷图是一个破伤风并非严重公共卫生问题的地区。
