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术后生活质量:“上消化道手术后功能障碍”评分系统的制定和验证。

Postoperative quality of life: development and validation of the "Dysfunction After Upper Gastrointestinal Surgery" scoring system.

机构信息

Department of Nursing, Jichi Medical University, Shimotsuke, Tochigi, Japan.

出版信息

J Am Coll Surg. 2011 Oct;213(4):508-14. doi: 10.1016/j.jamcollsurg.2011.07.007. Epub 2011 Aug 20.

DOI:10.1016/j.jamcollsurg.2011.07.007
PMID:21862356
Abstract

BACKGROUND

Although postoperative quality of life is an important outcomes measure, few tools exist to evaluate patients specifically after upper gastrointestinal surgery. The previously developed Dysfunction After Upper Gastrointestinal Surgery (DAUGS)32 scoring system has been further refined to include just 20 items. This study was undertaken to validate the refined evaluation tool.

STUDY DESIGN

The study was performed as a survey, administered to patients after upper gastrointestinal resection at 3 separate institutions.

RESULTS

The DAUGS20 score after gastrectomy (n = 662) was 27.8 and that after esophagectomy (n = 221) was 36.1, showing a significant difference (p < 0.05). The score after distal gastrectomy (n = 282) was 25.4 and that after total gastrectomy (n = 149) was 32.0, showing a significant (p < 0.05) difference. The α coefficient of all items on the DAUGS20 system was 0.904 and Cronbach's α coefficients of the subscales were 0.612 to 0.856, demonstrating high reliability of this evaluation tool. In addition, 7 factors were extracted from the 20 items using definitive factor analysis, to verify validity.

CONCLUSIONS

Patient quality of life should be evaluated as an outcomes measure after surgical resection for cancer, just as overall survival is analyzed. The DAUGS20 score is reliable, has validity in the evaluation of postoperative patients, and is a valuable tool to assess patient quality of life after upper gastrointestinal surgery for cancer.

摘要

背景

尽管术后生活质量是一个重要的结局衡量指标,但很少有工具专门用于评估上消化道手术后的患者。先前开发的上消化道手术后功能障碍(DAUGS)32 评分系统已进一步细化,仅包含 20 个项目。本研究旨在验证经过改进的评估工具。

研究设计

这项研究是一项调查,在 3 家不同的机构对接受上消化道切除术的患者进行了调查。

结果

胃切除术后的 DAUGS20 评分(n = 662)为 27.8,食管切除术(n = 221)后为 36.1,差异具有统计学意义(p < 0.05)。远端胃切除术(n = 282)后为 25.4,全胃切除术(n = 149)后为 32.0,差异具有统计学意义(p < 0.05)。DAUGS20 系统所有项目的α系数为 0.904,子量表的 Cronbach's α系数为 0.612 至 0.856,表明该评估工具具有很高的可靠性。此外,通过明确的因子分析从 20 个项目中提取了 7 个因子,以验证有效性。

结论

应该将患者的生活质量评估作为癌症手术切除后的结局衡量指标,就像分析总体生存率一样。DAUGS20 评分可靠,对评估术后患者具有有效性,是评估癌症上消化道手术后患者生活质量的一种有价值的工具。

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