Zhou Jing, Li Nanyun, Yang Guoyi, Zhu Yanfei
Department of Pathology, Wuxi People's Hospital of Nanjing Medical University, Wuxi, China.
Int J Surg Pathol. 2011 Dec;19(6):709-17. doi: 10.1177/1066896911417710. Epub 2011 Aug 23.
Multiple vascular patterns are presented in tumors of the central nervous system (CNS), including microvascular hyperplasia, branching capillaries, numerous capillaries without definite pattern, hyalinized vessels, and angiomatous area. These vascular patterns play important roles in pathological diagnosis of brain tumors. Because of insufficient recognition of the significance of the various vascular patterns, only a few of them have been applied in pathological diagnosis, leading to missed diagnosis and diagnostic errors. Microvascular hyperplasia can present in multiple brain tumors but display different diagnostic values. Otherwise, varied brain tumors characterized by branching capillaries or vascular pattern mimicking branching capillaries should be given careful consideration. Therefore, a familiarity of these tumors and their vascular pattern is essential for general pathologists. This study reviews the value of various kinds of vascular patterns for pathological diagnosis of brain tumors, constructs a framework for better understanding, and provides a novel perspective for general pathologists.
中枢神经系统（CNS）肿瘤呈现出多种血管模式，包括微血管增生、分支状毛细血管、无明确模式的大量毛细血管、玻璃样变血管以及血管瘤样区域。这些血管模式在脑肿瘤的病理诊断中发挥着重要作用。由于对各种血管模式的重要性认识不足，仅有少数几种血管模式应用于病理诊断，导致漏诊和诊断错误。微血管增生可出现在多种脑肿瘤中，但具有不同的诊断价值。此外，对于以分支状毛细血管或类似分支状毛细血管的血管模式为特征的各种脑肿瘤，应予以仔细考虑。因此，对于普通病理学家来说，熟悉这些肿瘤及其血管模式至关重要。本研究回顾了各种血管模式对脑肿瘤病理诊断的价值，构建了一个有助于更好理解的框架，并为普通病理学家提供了一个新的视角。
