18F-NaF PET 骨骼闪烁显像用于儿童骨痛评估。
Skeletal scintigraphy with 18F-NaF PET for the evaluation of bone pain in children.
机构信息
Department of Radiology, Children's Hospital, Boston, 300 Longwood Ave, Boston, MA 02115, USA.
出版信息
AJR Am J Roentgenol. 2011 Sep;197(3):713-9. doi: 10.2214/AJR.11.6670.
OBJECTIVE
Although not commonly used in current clinical practice, the PET agent (18)F-NaF provides an excellent alternative to the standard tracers used for radionuclide bone scintigraphy. This article illustrates the use and appearance of (18)F-NaF PET and shows examples of its utility in the assessment of bone pain in children.
CONCLUSION
Skeletal imaging with (18)F-NaF harnesses both the superior imaging characteristics of PET and the improved biodistribution of the fluoride tracer in comparison with standard nuclear techniques, resulting in excellent-quality images that can effectively be used to investigate the cause of bone pain in children.
目的
尽管在当前临床实践中并不常用，但 PET 示踪剂（18）F-NaF 为放射性核素骨闪烁显像中常用的标准示踪剂提供了极好的替代选择。本文介绍了（18）F-NaF PET 的使用和表现，并展示了其在评估儿童骨痛方面的应用实例。
结论
与标准核技术相比，（18）F-NaF 骨骼成像是对 PET 成像特性的充分利用，以及氟化物示踪剂在生物分布方面的改善，这使得其生成的高质量图像可有效用于调查儿童骨痛的病因。
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