• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

预防性误解作为参与和坚持使用杀微生物剂试验的动机:来自马拉维和津巴布韦的女性参与者和男性伴侣的证据。

Preventive misconception as a motivation for participation and adherence in microbicide trials: evidence from female participants and male partners in Malawi and Zimbabwe.

机构信息

International Partnership for Microbicides, Main Street 121, Paarl 7646, South Africa.

出版信息

AIDS Behav. 2012 Apr;16(3):785-90. doi: 10.1007/s10461-011-0027-7.

DOI:10.1007/s10461-011-0027-7
PMID:21863339
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3658446/
Abstract

This paper presents empirical data on motivation to join an HIV prevention trial of vaginal microbicide gels in Malawi and Zimbabwe, and participant assumption of a preventive misconception. Interviews were conducted with women participating in the trial and their male partners. Most of the female participants were able to adequately describe basic aspects of the trial design. HIV counseling and testing were primary reasons motivating women's participation, and male partners' support of the trial. 29% of women and 20% of men also provided indications of a preventive misconception, attributing gel use and trial participation to avoiding HIV infection.

摘要

本文提供了有关马拉维和津巴布韦女性参与阴道杀微生物剂凝胶艾滋病预防试验的动机和预防误解假设的经验数据。研究对参与试验的女性及其男性伴侣进行了访谈。大多数女性参与者能够充分描述试验设计的基本方面。艾滋病毒咨询和检测是促使女性参与试验的主要原因,也是男性伴侣支持试验的原因。29%的女性和 20%的男性也表示存在预防误解,认为使用凝胶和参与试验可以避免感染艾滋病毒。

相似文献

1
Preventive misconception as a motivation for participation and adherence in microbicide trials: evidence from female participants and male partners in Malawi and Zimbabwe.预防性误解作为参与和坚持使用杀微生物剂试验的动机:来自马拉维和津巴布韦的女性参与者和男性伴侣的证据。
AIDS Behav. 2012 Apr;16(3):785-90. doi: 10.1007/s10461-011-0027-7.
2
Preventive Misconception and Risk Behaviors in a Multinational HIV Prevention Trial.一项多国艾滋病预防试验中的预防误区与风险行为
AJOB Empir Bioeth. 2019 Apr-Jun;10(2):79-87. doi: 10.1080/23294515.2019.1593257. Epub 2019 Apr 19.
3
Male Partner Influence on Women's HIV Prevention Trial Participation and Use of Pre-exposure Prophylaxis: the Importance of "Understanding".男性伴侣对女性参与艾滋病病毒预防试验及使用暴露前预防药物的影响:“理解”的重要性
AIDS Behav. 2015 May;19(5):784-93. doi: 10.1007/s10461-014-0950-5.
4
Prevention, Partners, and Power Imbalances: Women's Views on How Male Partners Affected Their Adherence to Vaginal Microbicide Gels During HIV Prevention Trials in Africa.预防、伴侣和权力失衡:女性对男性伴侣如何影响其在非洲艾滋病毒预防试验中坚持使用阴道杀微生物凝胶的看法。
J Acquir Immune Defic Syndr. 2020 Dec 1;85(4):458-465. doi: 10.1097/QAI.0000000000002463.
5
Safety and effectiveness of BufferGel and 0.5% PRO2000 gel for the prevention of HIV infection in women.BufferGel 和 0.5% PRO2000 凝胶预防女性 HIV 感染的安全性和有效性。
AIDS. 2011 Apr 24;25(7):957-66. doi: 10.1097/QAD.0b013e32834541d9.
6
Topical microbicides for prevention of sexually transmitted infections.用于预防性传播感染的局部用杀微生物剂。
Cochrane Database Syst Rev. 2012 Jun 13(6):CD007961. doi: 10.1002/14651858.CD007961.pub2.
7
Trial participation disclosure and gel use behavior in the CAPRISA 004 tenofovir gel trial.CAPRISA 004替诺福韦凝胶试验中的试验参与披露及凝胶使用行为
AIDS Care. 2014;26(12):1521-5. doi: 10.1080/09540121.2014.938014.
8
Understanding women's motivations to participate in MTN-003/VOICE, a phase 2b HIV prevention trial with low adherence.了解女性参与MTN-003/VOICE(一项依从性较低的2b期HIV预防试验)的动机。
BMC Womens Health. 2019 Jan 25;19(1):18. doi: 10.1186/s12905-019-0713-6.
9
Relationship Type and Use of the Vaginal Ring for HIV-1 Prevention in the MTN 020/ASPIRE Trial.关系类型和阴道环在 MTN 020/ASPIRE 试验中预防 HIV-1 的使用。
AIDS Behav. 2020 Mar;24(3):866-880. doi: 10.1007/s10461-019-02521-9.
10
Long-term consistent use of a vaginal microbicide gel among HIV-1 sero-discordant couples in a phase III clinical trial (MDP 301) in rural south-west Uganda.在乌干达西南部农村地区开展的一项 III 期临床试验(MDP 301)中,艾滋病毒 1 型血清不一致的夫妇长期持续使用阴道杀微生物凝胶。
Trials. 2013 Feb 1;14:33. doi: 10.1186/1745-6215-14-33.

引用本文的文献

1
Expectations of preventative benefits and risk behaviors in a randomized trial evaluating oral HIV preexposure prophylaxis candidates.评价口服 HIV 暴露前预防候选药物的随机试验中对预防益处和风险行为的期望。
AIDS Care. 2024 Aug;36(8):1172-1178. doi: 10.1080/09540121.2024.2332446. Epub 2024 Apr 12.
2
Influences on clinical trial participation: Enhancing recruitment through a gender lens - A scoping review.对临床试验参与的影响:通过性别视角加强招募——一项范围综述
Contemp Clin Trials Commun. 2024 Feb 29;38:101283. doi: 10.1016/j.conctc.2024.101283. eCollection 2024 Apr.
3
Does the Ring Work? Perceptions and Understanding of the Efficacy of a Dapivirine Vaginal Ring for HIV Prevention Amongst Women in a Placebo-Controlled Trial.该环有效吗?在安慰剂对照试验中,女性对双汰芝阴道环预防艾滋病毒效果的看法和理解。
AIDS Behav. 2022 May;26(5):1597-1606. doi: 10.1007/s10461-021-03512-5. Epub 2021 Nov 2.
4
Adolescent perceptions about participating in HIV-related research studies.青少年对参与艾滋病相关研究的看法。
Child Youth Serv Rev. 2020 Sep;116. doi: 10.1016/j.childyouth.2020.105262. Epub 2020 Jul 18.
5
Preventive Misconception and Risk Behaviors in a Multinational HIV Prevention Trial.一项多国艾滋病预防试验中的预防误区与风险行为
AJOB Empir Bioeth. 2019 Apr-Jun;10(2):79-87. doi: 10.1080/23294515.2019.1593257. Epub 2019 Apr 19.
6
The willingness to participate in biomedical research involving human beings in low- and middle-income countries: a systematic review.在中低收入国家参与涉及人类的生物医学研究的意愿:系统评价。
Trop Med Int Health. 2019 Mar;24(3):264-279. doi: 10.1111/tmi.13195. Epub 2019 Jan 8.
7
"Free Testing and PrEP without Outing Myself to Parents:" Motivation to participate in oral and injectable PrEP clinical trials among adolescent men who have sex with men.“免费检测和 PrEP,不向父母出柜”:男男性行为青少年参与口服和注射 PrEP 临床试验的动机。
PLoS One. 2018 Jul 25;13(7):e0200560. doi: 10.1371/journal.pone.0200560. eCollection 2018.
8
Using Cognitive Interviews to Enhance Measurement in Empirical Bioethics: Developing a Measure of the Preventive Misconception in Biomedical HIV Prevention Trials.运用认知访谈提升实证生物伦理学中的测量:开发一项关于生物医学HIV预防试验中预防性误解的测量指标。
AJOB Empir Bioeth. 2016;7(1):17-23. doi: 10.1080/23294515.2015.1037967. Epub 2015 May 1.
9
The promise and peril of pre-exposure prophylaxis (PrEP): using social science to inform prep interventions among female sex workers.暴露前预防(PrEP)的前景与风险:运用社会科学为女性性工作者的PrEP干预提供信息
Afr J Reprod Health. 2014 Sep;18(3 Spec No):74-83.
10
Characteristics Associated with HIV Drug Resistance Among Women Screening for an HIV Prevention Trial in KwaZulu-Natal, South Africa.南非夸祖鲁-纳塔尔省一项艾滋病预防试验筛查中女性群体的艾滋病病毒耐药性相关特征
AIDS Behav. 2015 Nov;19(11):2076-86. doi: 10.1007/s10461-015-1056-4.

本文引用的文献

1
Safety and effectiveness of BufferGel and 0.5% PRO2000 gel for the prevention of HIV infection in women.BufferGel 和 0.5% PRO2000 凝胶预防女性 HIV 感染的安全性和有效性。
AIDS. 2011 Apr 24;25(7):957-66. doi: 10.1097/QAD.0b013e32834541d9.
2
Blockage and flow: intimate experiences of condoms and microbicides in a South African clinical trial.阻塞与流动:南非临床试验中对避孕套和杀微生物剂的亲密体验。
Cult Health Sex. 2011 Jan;13(1):31-44. doi: 10.1080/13691058.2010.511270.
3
Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women.替诺福韦凝胶作为一种抗逆转录病毒的杀微生物剂,用于预防女性感染艾滋病毒的有效性和安全性。
Science. 2010 Sep 3;329(5996):1168-74. doi: 10.1126/science.1193748. Epub 2010 Jul 19.
4
Acceptability and adherence of a candidate microbicide gel among high-risk women in Africa and India.在非洲和印度的高风险女性中,候选杀微生物凝胶的可接受性和依从性。
Cult Health Sex. 2010 Oct;12(7):739-54. doi: 10.1080/13691051003728599.
5
Preventive misconception: its nature, presence, and ethical implications for research.预防性误解:其本质、存在情况及其对研究的伦理影响。
Am J Prev Med. 2007 May;32(5):370-4. doi: 10.1016/j.amepre.2007.01.007.
6
Male circumcision in Siaya and Bondo Districts, Kenya: prospective cohort study to assess behavioral disinhibition following circumcision.肯尼亚锡亚亚区和邦多区的男性包皮环切术:评估包皮环切术后行为抑制的前瞻性队列研究。
J Acquir Immune Defic Syndr. 2007 Jan 1;44(1):66-70. doi: 10.1097/01.qai.0000242455.05274.20.
7
"We have our protector": misperceptions of protection against HIV among participants in a microbicide efficacy trial.“我们有了保护措施”:在一项杀微生物剂功效试验中参与者对预防艾滋病病毒的误解
Am J Public Health. 2006 Jun;96(6):1073-7. doi: 10.2105/AJPH.2004.047514. Epub 2006 May 2.
8
Undue inducement in clinical research in developing countries: is it a worry?发展中国家临床研究中的不当诱导:这是一个值得担忧的问题吗?
Lancet. 2005;366(9482):336-40. doi: 10.1016/S0140-6736(05)66992-9.
9
Increase in sexual risk behavior associated with immunologic response to highly active antiretroviral therapy among HIV-infected injection drug users.感染人类免疫缺陷病毒(HIV)的注射吸毒者中,与高效抗逆转录病毒治疗的免疫反应相关的性风险行为增加。
Clin Infect Dis. 2004 Apr 15;38(8):1167-74. doi: 10.1086/383033. Epub 2004 Apr 5.
10
Shifts in condom use following microbicide introduction: should we be concerned?引入杀微生物剂后避孕套使用情况的变化:我们应该担心吗?
AIDS. 2003 May 23;17(8):1227-37. doi: 10.1097/00002030-200305230-00015.