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AIDS Behav. 2018 Feb;22(2):437-446. doi: 10.1007/s10461-017-1977-1.
2
Acceptability and use of a dapivirine vaginal ring in a phase III trial.达匹韦林阴道环在一项III期试验中的可接受性及使用情况。
AIDS. 2017 May 15;31(8):1159-1167. doi: 10.1097/QAD.0000000000001452.
3
Safety, Acceptability and Adherence of Dapivirine Vaginal Ring in a Microbicide Clinical Trial Conducted in Multiple Countries in Sub-Saharan Africa.在撒哈拉以南非洲多个国家开展的一项杀微生物剂临床试验中,达匹韦林阴道环的安全性、可接受性及依从性
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Social Context of Adherence in an Open-Label 1 % Tenofovir Gel Trial: Gender Dynamics and Disclosure in KwaZulu-Natal, South Africa.一项开放标签的1%替诺福韦凝胶试验中依从性的社会背景:南非夸祖鲁-纳塔尔省的性别动态与信息披露
AIDS Behav. 2016 Nov;20(11):2682-2691. doi: 10.1007/s10461-016-1339-4.
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Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women.使用含达匹韦林的阴道环预防女性感染HIV-1。
N Engl J Med. 2016 Dec 1;375(22):2121-2132. doi: 10.1056/NEJMoa1506110. Epub 2016 Feb 22.
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The Promise of Intravaginal Rings for Prevention: User Perceptions of Biomechanical Properties and Implications for Prevention Product Development.阴道环用于预防的前景:使用者对生物力学特性的认知及其对预防产品开发的启示
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To tell or not to tell: male partner engagement in a Phase 3 microbicide efficacy trial in South Africa.告知还是不告知:南非一项三期杀微生物剂疗效试验中的男性伴侣参与情况。
Cult Health Sex. 2015;17(8):1004-20. doi: 10.1080/13691058.2015.1030451. Epub 2015 Apr 27.
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Acceptability and preferences for vaginal dosage forms intended for prevention of HIV or HIV and pregnancy.用于预防 HIV 或 HIV 和妊娠的阴道剂型的可接受性和偏好。
Adv Drug Deliv Rev. 2015 Sep 15;92:146-54. doi: 10.1016/j.addr.2015.02.004. Epub 2015 Feb 19.
9
Male Partner Influence on Women's HIV Prevention Trial Participation and Use of Pre-exposure Prophylaxis: the Importance of "Understanding".男性伴侣对女性参与艾滋病病毒预防试验及使用暴露前预防药物的影响:“理解”的重要性
AIDS Behav. 2015 May;19(5):784-93. doi: 10.1007/s10461-014-0950-5.
10
Engaging male partners in women's microbicide use: evidence from clinical trials and implications for future research and microbicide introduction.让男性伴侣参与女性使用杀微生物剂:临床试验证据及其对未来研究和杀微生物剂推广的意义。
J Int AIDS Soc. 2014 Sep 8;17(3 Suppl 2):19159. doi: 10.7448/IAS.17.3.19159. eCollection 2014.

关系类型和阴道环在 MTN 020/ASPIRE 试验中预防 HIV-1 的使用。

Relationship Type and Use of the Vaginal Ring for HIV-1 Prevention in the MTN 020/ASPIRE Trial.

机构信息

RTI International, Women's Global Health Imperative, UC Berkeley SPH, 628 Beacon Street, Oakland, CA, 94610, USA.

University of Zimbabwe-University of California San Francisco Collaborative Research Program (UZ-UCSF), San Francisco, CA, USA.

出版信息

AIDS Behav. 2020 Mar;24(3):866-880. doi: 10.1007/s10461-019-02521-9.

DOI:10.1007/s10461-019-02521-9
PMID:31111297
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6864230/
Abstract

Gender roles and imbalances in sexual power contribute to the heightened HIV-1 risk faced by women in Sub-Saharan Africa. This has led prevention research to focus on the development of female controlled methods. Despite the design of products such as vaginal rings to be used autonomously by women, male partners and women's perceptions of relationships influence HIV prevention choices. To understand the influences that male partners and dyadic dynamics had on the use of the Dapivirine Vaginal Ring in the ASPIRE trial, this analysis of qualitative data explored the types of intimate partner relationships that women engaged in. This paper describes how partners facilitated or challenged women's ring use and how women dealt with these challenges within six different types of relationships characterized by power dynamics and commitment levels. We offer insights into how future use of female-initiated HIV prevention products can be promoted through recognition of different relationship types.

摘要

性别角色和性权力的不平衡导致撒哈拉以南非洲的女性面临更高的 HIV-1 风险。这促使预防研究的重点转向开发女性控制的方法。尽管设计了阴道环等产品供女性自主使用,但男性伴侣和女性对关系的看法会影响 HIV 预防选择。为了了解男性伴侣和对偶动态对 ASPIRE 试验中使用 dapivirine 阴道环的影响,对定性数据的分析探讨了女性参与的亲密伴侣关系的类型。本文描述了伴侣如何促进或挑战女性使用避孕环,以及女性如何在六种不同类型的关系中应对这些挑战,这些关系的特点是权力动态和承诺水平。我们提供了有关如何通过识别不同的关系类型来促进未来使用女性主导的 HIV 预防产品的见解。