胃癌的临床管理：多中心调查结果。
Clinical management of gastric cancer: results of a multicentre survey.
机构信息
The Department of Medical Oncology, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University; No, 37, Guo Xue Xiang, Chengdu, Sichuan, 610041, China.
出版信息
BMC Cancer. 2011 Aug 24;11:369. doi: 10.1186/1471-2407-11-369.
BACKGROUND
The National Comprehensive Cancer Network clinical practice guidelines in oncology-gastric cancer guidelines have been widely used to provide appropriate recommendations for the treatment of patients with gastric cancer. The aim of this study was to examine the adherence of surgical oncologists, medical oncologists, and radiation oncologists' to the recommended guidelines.
METHODS
A questionnaire asking the treatment options for gastric cancer cases was sent to 394 Chinese oncology specialists, including surgical oncologists, medical oncologists, and radiation oncologists working in hospitals joined in The Western Cooperative Gastrointestinal Oncology Group of China. The questionnaire involved a series of clinical scenarios regarding the interpretation of surgery, neoadjuvant, adjuvant, and advanced treatment planning of gastric cancer.
RESULTS
Analysis of 358 respondents (91%) showed variations between each specialization and from the recommended guidelines in the management approaches to specific clinical scenarios. The majority of specialists admitted that less than 50% of patients received multidisciplinary evaluation before treatment. The participants gave different responses to questions involving adjuvant, neoadjuvant, and advanced settings, compared to the recommended guidelines.
CONCLUSIONS
These results highlight the heterogeneity of the treatment of gastric cancer. Surgical oncologists, medical oncologists, and radiation oncologists are not adhering to the recommended guidelines.
背景
国家综合癌症网络（National Comprehensive Cancer Network，NCCN）肿瘤临床实践指南中的胃癌指南被广泛用于为胃癌患者的治疗提供适当的建议。本研究旨在调查外科肿瘤学家、内科肿瘤学家和放射肿瘤学家对推荐指南的遵循情况。
方法
向 394 名在中国西部协作胃肠肿瘤组（Western Cooperative Gastrointestinal Oncology Group of China）合作医院工作的中国肿瘤学专家（包括外科肿瘤学家、内科肿瘤学家和放射肿瘤学家）发送了一份关于胃癌病例治疗选择的问卷。问卷涉及一系列有关胃癌手术、新辅助治疗、辅助治疗和晚期治疗计划的临床情景。
结果
对 358 名（91%）应答者的分析显示，每个专业之间以及与推荐指南之间在特定临床情景的管理方法上存在差异。大多数专家承认，在治疗前，不到 50%的患者接受了多学科评估。与推荐指南相比，参与者对涉及辅助、新辅助和晚期治疗的问题给出了不同的回答。
结论
这些结果突出了胃癌治疗的异质性。外科肿瘤学家、内科肿瘤学家和放射肿瘤学家并未遵循推荐的指南。
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