Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, NSW, Australia.
Am J Kidney Dis. 2011 Nov;58(5):704-16. doi: 10.1053/j.ajkd.2011.05.029. Epub 2011 Aug 23.
Deceased donor kidneys are a scarce resource and there is debate about how to maximize the benefit from each donated kidney while ensuring equity of access to transplants. Allocation of kidneys to waitlisted patients is determined by a computer algorithm, but the decision to waitlist patients or accept the kidneys offered is largely at the discretion of nephrologists. This study aims to elicit nephrologists' perspectives on waitlisting patients for kidney transplant and the allocation of deceased kidneys.
We conducted semistructured face-to-face interviews with adult and pediatric nephrologists from 15 Australian nephrology or transplant centers. Transcripts were analyzed for descriptive and analytical themes.
25 nephrologists participated. 5 major themes on waitlisting and deceased donor kidney allocation were identified: patient advocacy (championing their own patients, empowering patients, giving hope, individualizing judgments, patient preferences, and limited autonomy), professional and moral integrity (transparency, avoiding value judgments, and eliminating bias), protecting center reputation (gatekeeping), achieving equity (uniformity, avoiding discrimination, and fairness for specific populations), and maximizing societal benefit (prioritizing best use of kidney, resource implications, favoring social contribution, and improving efficiency of the allocation process). In making individual patient assessments, estimates about outcomes for a patient had to be resolved with whether it was reasonable from a broader societal perspective.
Nephrologists expressed their primary responsibility in terms of giving their own patients access to a transplant and upholding professional integrity by maintaining transparency and avoiding value judgments and bias. However, nephrologists perceived an obligation to protect their center's reputation through the selection of "good" patients, and this caused some frustration. Despite having personal preferences for optimizing the balance between societal benefit and equity, nephrologists did not want direct responsibility for ensuring societal benefit in clinical practice. Rather, they placed the onus on policy makers and the community to reconcile such tensions and advocate for societal benefit.
已故供体的肾脏是一种稀缺资源,如何在确保移植公平性的同时最大限度地提高每个捐献肾脏的效益,这存在争议。肾脏分配给候补患者是由计算机算法决定的,但候补患者的决定或接受提供的肾脏在很大程度上取决于肾病学家的判断。本研究旨在征求肾病学家对候补患者进行肾脏移植和分配已故供体肾脏的看法。
我们对来自澳大利亚 15 个肾病学或移植中心的成人和儿科肾病学家进行了半结构化的面对面访谈。对访谈记录进行了描述性和分析性主题分析。
共有 25 名肾病学家参与。确定了 5 个关于候补和已故供体肾脏分配的主要主题:患者倡导(为自己的患者辩护,赋予患者权力,给予希望,个体化判断,患者偏好和有限的自主权),专业和道德操守(透明,避免价值判断和消除偏见),保护中心声誉(把关),实现公平(一致性,避免歧视和对特定人群的公平),以及最大限度地提高社会效益(优先考虑肾脏的最佳利用,资源影响,支持社会贡献和提高分配过程的效率)。在对个别患者进行评估时,必须根据更广泛的社会观点来解决对患者结果的估计是否合理。
肾病学家表示,他们的主要责任是让自己的患者获得移植,并通过保持透明,避免价值判断和偏见来维护专业操守。但是,肾病学家认为有责任通过选择“好”患者来保护他们中心的声誉,这引起了一些不满。尽管对优化社会效益与公平之间的平衡有个人偏好,但肾病学家并不希望在临床实践中直接负责确保社会效益。相反,他们将责任推给政策制定者和社区,以调和这些紧张关系并倡导社会效益。