Pantiavin A A, Isheeva A K, Artiukhov V G
Radiats Biol Radioecol. 2011 May-Jun;51(3):352-6.
The purpose of the present work is to study the vacuum ultraviolet radiation action on the optical and chromatographic characteristics of human hemoglobin molecules and their components - haem and globin. Using the methods of spectrophotometry and thin layer chromatography (TLC), we have investigated into the structural changes of molecules of human hemoglobin, haem and globin, induced by the influence of vacuum UV light (gamma = 118-134 nm, dose - 1.2 kJ/m2). It has been shown that vacuum ultraviolet radiation induces an infringement of the higher types of the spatial organization ofglobin molecules, thus leading to the changes in the structural state of the albuminous globule.
本研究的目的是探讨真空紫外辐射对人血红蛋白分子及其组分——血红素和球蛋白的光学和色谱特性的影响。采用分光光度法和薄层色谱法（TLC），我们研究了真空紫外光（γ = 118 - 134 nm，剂量 - 1.2 kJ/m²）对人血红蛋白、血红素和球蛋白分子结构变化的影响。结果表明，真空紫外辐射会破坏球蛋白分子的高级空间组织类型，从而导致白蛋白球结构状态的改变。
