Leyden J J
University of Pennsylvania School of Medicine, Philadelphia 19104.
Br J Dermatol. 1990 Apr;122 Suppl 35:1-3. doi: 10.1111/j.1365-2133.1990.tb16118.x.
Ageing of the skin involves the intrinsic process of senescence and extrinsic damage induced by chronic exposure to UV radiation. A recent consensus forum of the American Academy of Dermatology concluded that the majority of undesirable clinical features associated with 'skin ageing' are the result of damage to skin due to UV radiation (photoageing). Clinically photoageing is characterized by coarseness, wrinkling, mottled pigmentation, laxity, telangiectasia, and premalignant and malignant neoplasms. The role of genetics, hormones and diet needs to be clarified. Appropriate lifelong use of sunscreens may minimize many of the changes associated with photoageing.
皮肤老化涉及衰老的内在过程以及长期暴露于紫外线辐射所导致的外在损伤。美国皮肤科学会最近的一次共识论坛得出结论，与“皮肤老化”相关的大多数不良临床特征是紫外线辐射对皮肤造成损伤（光老化）的结果。临床上，光老化的特征表现为皮肤粗糙、起皱、色素沉着斑驳、皮肤松弛、毛细血管扩张以及癌前和恶性肿瘤。遗传学、激素和饮食的作用尚需阐明。适当终身使用防晒霜可能会将许多与光老化相关的变化降至最低。
