Department of Molecular Immunology, Faculty of Biology, BIOSS Centre for Biological Signalling Studies, Center for Chronic Immunodeficiency (CCI) and Max-Planck-Institute for Immunbiology and Epigenetics, Stübeweg 51, 79108 Freiburg, Germany.
Immunity. 2011 Aug 26;35(2):151-3. doi: 10.1016/j.immuni.2011.08.004.
In the current issue of Immunity, Martínez-Martín et al. (2011) describe the central supramolecular activation cluster (cSMAC) as a site of clathrin-independent T cell receptor (TCR) internalization and trogocytosis. Further, they identify small Rho GTPases TC21 and RhoG as key mediators of these processes.
在本期《免疫》中，Martínez-Martín 等人（2011 年）将中央超分子激活簇（cSMAC）描述为网格蛋白非依赖性 T 细胞受体（TCR）内化和trogoctosis 的部位。此外，他们还确定了小 Rho GTPases TC21 和 RhoG 是这些过程的关键介质。
