利用溶解纤维素的离子液体从银杏叶中提取和分离莽草酸。
Extraction and isolation of shikimic acid from Ginkgo biloba leaves utilizing an ionic liquid that dissolves cellulose.
机构信息
Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, Tokyo 102-8554, Japan.
出版信息
Chem Commun (Camb). 2011 Oct 14;47(38):10560-2. doi: 10.1039/c1cc13306c. Epub 2011 Aug 25.
PMID:21869955
Abstract
Shikimic acid, the starting material in the commercial synthesis of oseltamivir phosphate (Tamiflu®), was efficiently extracted and isolated from Ginkgo biloba leaves utilizing the ionic liquid 1-butyl-3-methylimidazolium chloride ([bmim]Cl), which dissolves cellulose.
摘要
利用溶解纤维素的离子液体 1-丁基-3-甲基咪唑氯([bmim]Cl)，从银杏叶中高效提取和分离了用于奥司他韦磷酸盐（达菲）商业合成的起始原料莽草酸。
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