Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioicho, Chiyoda-ku, Tokyo, 102-8554, Japan.
Sci Rep. 2017 Jul 31;7(1):6890. doi: 10.1038/s41598-017-07291-9.
Sweet potato, Ipomoea batatas, is a widely cultivated vegetable worldwide. The leaves contain polyphenolic natural products called caffeoylquinic acids (CQAs), which possess biological activities including inhibition of aggregation of amyloid peptides. The present study describes an efficient extraction and isolation procedure for CQAs from sweet potato leaves using a cellulose-dissolving ionic liquid. The results showed that, compared to methanol, use of 1-butyl-3-methylimidazolium chloride ([Cmim]Cl) allowed the extraction of a 6.5-fold greater amount of CQAs. This protocol will enable the efficient extraction of other organic compounds and biopolymers from natural materials.
甘薯，Ipomoea batatas，是一种在全球范围内广泛种植的蔬菜。其叶子含有多酚类天然产物，称为咖啡酰奎宁酸（CQAs），具有抑制淀粉样肽聚集等生物活性。本研究描述了一种使用纤维素溶解离子液体从甘薯叶中高效提取和分离 CQAs 的方法。结果表明，与甲醇相比，使用 1-丁基-3-甲基咪唑氯（[Cmim]Cl）可使 CQAs 的提取量增加 6.5 倍。该方案将能够从天然材料中有效提取其他有机化合物和生物聚合物。
