将金纳米粒子程序性地放置在狭缝型 DNA 折纸支架上。
Programmed placement of gold nanoparticles onto a slit-type DNA origami scaffold.
机构信息
Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Yoshida-ushinomiyacho, Kyoto 606-8501, Japan.
出版信息
Chem Commun (Camb). 2011 Oct 14;47(38):10743-5. doi: 10.1039/c1cc13984c. Epub 2011 Aug 24.
PMID:21869958
Abstract
A novel DNA scaffold, called a DNA slit, was designed for the programmed positioning of Au nanoparticles (AuNPs), and various patterns of thiolated DNA slits were constructed. AuNPs were correctly placed at the predesigned positions in the thiolated DNA slits, indicating that the thiolated staples and the slit cavities guide the correct assembly of AuNPs.
摘要
设计了一种新型的 DNA 支架，称为 DNA 狭缝，用于 Au 纳米粒子（AuNPs）的程序化定位，并构建了各种巯基化 DNA 狭缝图案。AuNPs 被正确地放置在巯基化 DNA 狭缝的预定位置，表明巯基化的订书钉和狭缝腔引导 AuNPs 的正确组装。
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