Voineag Monica, Drug V, Indrei L L, Cobzeanu M D
Universităţii de Medicină şi Farmacie Gr. T. Popa Iaşi Centrul de Diagnostic şi Tratament Dr. Victor Babeş Bucureşti Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi.
Rev Med Chir Soc Med Nat Iasi. 2011 Apr-Jun;115(2):405-11.
Pharyngolaryngeal reflux (PLR) refers to backflow of stomach contents into the throat and larynx. Its diagnosis is difficult because of a variety of atypical symptoms, low sensitivity of traditional tests of gastrointestinal tract, and no consensus on the diagnostic algorithm. The aim of this study was to provide an algorithm for the diagnosis and treatment of PLR. There were no pathognomonic symptoms or findings, but the characteristic symptoms validate the Reflux Symptom Index and Reflux Findings Score as tools in the initial diagnosis. The first approach is empirical medical treatment for 3 month, based on endoscopic findings at laryngofiberscopy; then objective demonstration of reflux events using multichannel intraluminal impedance and pH monitoring. Proton pump inhibitors represent the mainstay of therapy for the patients with PLR, but they require a more aggressive and prolonged treatment than the patients with gastroesophageal symptoms.
咽喉反流(PLR)是指胃内容物反流至咽喉部。由于其存在多种非典型症状、传统胃肠道检查的敏感性较低以及诊断算法尚无共识,故其诊断较为困难。本研究的目的是提供一种PLR的诊断和治疗算法。虽然没有特异性症状或体征,但特征性症状可验证反流症状指数和反流发现评分作为初始诊断工具的有效性。第一种方法是根据纤维喉镜检查的内镜表现进行为期3个月的经验性药物治疗;然后使用多通道腔内阻抗和pH监测客观证明反流事件。质子泵抑制剂是PLR患者治疗的主要药物,但与有胃食管症状的患者相比,他们需要更积极、更长期的治疗。