Department of Obstetrics and Gynecology, VU University Medical Center, Amsterdam, The Netherlands.
J Perinat Med. 2011 Sep;39(5):605-10. doi: 10.1515/jpm.2011.070. Epub 2011 Aug 28.
The objective of this study was to assess whether the incidence of neonatal morbidity of neonates born at term and admitted to a neonatal intensive care unit (NICU) differs by gestational age and level of care.
This is a 5-year retrospective cohort study of singleton term births admitted to the NICU of the VU University Medical Center with a gestational age ≥37+0 weeks.
In total, 497 neonates were included in the study. The incidence of neonates born with an arterial cord blood pH<7.10, neonatal asphyxia, and meconium aspiration syndrome increased with advancing gestational age. The incidence of secondary cesarean section and operative vaginal delivery also increased with advancing gestational age. Neonatal death occurred in 29 (5.84%) of the 497 cases; 27 (93%) of 29 were due to asphyxia. Seventeen (34%) of the 50 neonates born in primary care were admitted for asphyxia. Eight (47%) of these 17 neonates died.
Neonatal morbidity in term neonates is related to gestational age at birth. Since asphyxia is an important cause of both morbidity and mortality in term neonates, it is important to clearly define and include asphyxia in future perinatal audits.
本研究旨在评估足月新生儿在新生儿重症监护病房(NICU)的发病率是否因胎龄和护理水平而异。
这是一项对在 VU 大学医学中心 NICU 住院的胎龄≥37+0 周的单胎足月新生儿进行的 5 年回顾性队列研究。
共纳入 497 例新生儿。随着胎龄的增加,出生时动脉脐带血 pH 值<7.10、新生儿窒息和胎粪吸入综合征的发生率增加。继发性剖宫产和经阴道分娩的发生率也随胎龄的增加而增加。497 例病例中发生新生儿死亡 29 例(5.84%);27 例(93%)死亡是由于窒息。50 例在初级保健中出生的新生儿中有 17 例因窒息入院。这 17 例新生儿中有 8 例(47%)死亡。
足月新生儿的发病率与出生时的胎龄有关。由于窒息是足月新生儿发病率和死亡率的重要原因,因此在未来的围产儿审计中明确定义并包括窒息非常重要。