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预防一名16岁男孩颈椎侵袭性动脉瘤样骨囊肿复发的治疗选择——病例报告

Therapeutic options to prevent recurrence of an aggressive aneurysmatic bone cyst of the cervical spine of a 16 year old boy - a case report.

作者信息

Richter Juliane, Tschöke Sven K, Gulow Jens, Eichfeld Uwe, Wojan Magdalena, von Salis-Soglio Georg, Heyde Christoph E

机构信息

Department of Orthopaedic Surgery, University Hospital Leipzig, Liebigstr. 20, 04103 Leipzig, Germany.

Department of Abdominal, Transplant, Vascular and Thoracic Surgery, University Hospital Leipzig, Liebigstr. 20, 04103 Leipzig, Germany.

出版信息

Patient Saf Surg. 2011 Aug 26;5(1):20. doi: 10.1186/1754-9493-5-20.

DOI:10.1186/1754-9493-5-20
PMID:21871055
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3177761/
Abstract

The aneurysmatic bone cyst (ABC) is a benign primary bone tumour. If located in the cervical spine, its expansive growth and destructive behaviour may lead to instability and serious neurological impairment. We report a case of a 16-year-old boy with an aggressive ABC in the 7th cervical vertebra. Computertomographic and magnetic resonance imaging revealed the envelopment of the left 7th and 8th spinal nerve along with the anterior displacement of the left vertebral artery. The interdisciplinary surgical strategy consisted of a partially incomplete cyst resection, subtotal spondylectomy with posterior screw-and-rod fixation from C6-Th1, iliac crest bone grafting and anterior plating from C6-Th1. With regard to the high rate of recurrence after incomplete resection published in the recent literature, the patient was postoperatively treated by megavoltage radiotherapy with a total dose of 30Gy (daily dose of 1.8 Gy for 3 weeks). The clinical and radiographic follow-up showed complete recovery of all neurologic impairments and no signs of tumour recurrence at 3, 6 and 12 months after surgery. This case highlights diverse treatment regimens and shall outline the challenge and the problems of the interdisciplinary decision-making in adolescents presenting with ABC in high-demanding anatomical regions.

摘要

动脉瘤样骨囊肿(ABC)是一种良性原发性骨肿瘤。如果位于颈椎,其膨胀性生长和破坏性行为可能导致不稳定和严重的神经功能损害。我们报告一例16岁男孩,其第7颈椎有侵袭性ABC。计算机断层扫描和磁共振成像显示左第7和第8脊神经被包绕,同时左椎动脉向前移位。多学科手术策略包括部分不完全囊肿切除术、C6至Th1的次全椎体切除及后路螺钉棒固定、髂嵴植骨和C6至Th1前路钢板固定。鉴于近期文献报道不完全切除后复发率较高,患者术后接受了总剂量30Gy的兆伏级放疗(3周内每日剂量1.8Gy)。临床和影像学随访显示,术后3、6和12个月时所有神经功能损害完全恢复,无肿瘤复发迹象。该病例突出了多种治疗方案,并应概述在高要求解剖区域出现ABC的青少年多学科决策的挑战和问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e60/3177761/999a11768dc9/1754-9493-5-20-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e60/3177761/e15cb495ae74/1754-9493-5-20-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e60/3177761/76de2583a76f/1754-9493-5-20-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e60/3177761/17e3d4773595/1754-9493-5-20-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e60/3177761/3c0bd1d4ee67/1754-9493-5-20-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e60/3177761/999a11768dc9/1754-9493-5-20-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e60/3177761/e15cb495ae74/1754-9493-5-20-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e60/3177761/76de2583a76f/1754-9493-5-20-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e60/3177761/17e3d4773595/1754-9493-5-20-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e60/3177761/3c0bd1d4ee67/1754-9493-5-20-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e60/3177761/999a11768dc9/1754-9493-5-20-5.jpg

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