11岁男孩颈椎侵袭性骨母细胞瘤伴继发性动脉瘤样骨囊肿：病例报告
Destructive osteoblastoma with secondary aneurysmal bone cyst of cervical vertebra in an 11-year-old boy: case report.
作者信息
Hu Hongtao, Wu Jianxin, Ren Liang, Sun Xianze, Li Feng, Ye Xiaojian
机构信息
Department of Orthopaedics, Shijiazhuang No. 3 Hospital Shijiazhuang, China.
Department of Orthopaedics, The No. 411 Hospital Shanghai, China.
出版信息
Int J Clin Exp Med. 2014 Jan 15;7(1):290-5. eCollection 2014.
STUDY DESIGN
A case report and review of previous literature are presented.
OBJECTIVE AND BACKGROUND
The objective of this manuscript was to report a case of destructive osteoblastoma with secondary aneurysmal bone cyst of cervical vertebra in a child, and discuss the pathogenesis of this disease. The combination of osteoblastoma and aneurysmal bone cyst in the cervical spine is rare in primary bone neoplasm. To the authors' knowledge, only one case in a child has been reported.
METHOD
Plain X-rays, technetium bone scanning, CT scan and MRI indicated an expansile, partially sclerotic lesion of the C4 involving the body of vertebra and appendix. The lesion was excised through anterior and posterior approach.
RESULTS
After operation the tumor was removed completely. There has been no sign of tumor recurrence or clinical or radiologic sign of instability in the follow-up investigations.
CONCLUSIONS
We report a rare case of destructive osteoblastoma with Secondary aneurysmal bone cyst of cervical vertebra in a child, a full investigation indicated that complete resection of the tumor can prevent recurrence and malignant transformation. Long-term follow-up is needed to declare a lifelong cure of the disease.
研究设计
本文呈现了一例病例报告及对既往文献的回顾。
目的与背景
本手稿的目的是报告一例儿童颈椎侵袭性成骨细胞瘤伴继发性骨囊肿病例，并探讨该疾病的发病机制。颈椎成骨细胞瘤与骨囊肿的组合在原发性骨肿瘤中较为罕见。据作者所知，仅报道过一例儿童病例。
方法
X线平片、骨扫描、CT扫描及MRI显示C4椎体有一膨胀性、部分硬化性病变，累及椎体及附件。通过前后路联合手术切除病变。
结果
术后肿瘤被完全切除。在随访检查中，未发现肿瘤复发迹象，也无临床或影像学不稳定表现。
结论
我们报告了一例罕见的儿童颈椎侵袭性成骨细胞瘤伴继发性骨囊肿病例，全面检查表明肿瘤的完全切除可预防复发和恶变。需要长期随访以宣布该疾病的终身治愈。
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