OXTR基因rs2254298对健康白种成年人边缘系统的神经遗传学影响。 - Suppr

Neurogenetic effects of OXTR rs2254298 in the extended limbic system of healthy Caucasian adults.

作者信息

Tost Heike, Kolachana Bhaskar, Verchinski Beth A, Bilek Edda, Goldman Aaron L, Mattay Venkata S, Weinberger Daniel R, Meyer-Lindenberg Andreas

出版信息

Biol Psychiatry. 2011 Nov 1;70(9):e37-9; author reply e41-2. doi: 10.1016/j.biopsych.2011.06.034. Epub 2011 Aug 27.

DOI:10.1016/j.biopsych.2011.06.034

PMID:21872215

Abstract

摘要

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Neurogenetic effects of OXTR rs2254298 in the extended limbic system of healthy Caucasian adults.OXTR基因rs2254298对健康白种成年人边缘系统的神经遗传学影响。

Biol Psychiatry. 2011 Nov 1;70(9):e37-9; author reply e41-2. doi: 10.1016/j.biopsych.2011.06.034. Epub 2011 Aug 27.

Association between the oxytocin receptor gene and amygdalar volume in healthy adults.健康成年人催产素受体基因与杏仁核体积的关联。

Biol Psychiatry. 2010 Dec 1;68(11):1066-72. doi: 10.1016/j.biopsych.2010.07.019. Epub 2010 Sep 15.

Amygdala responses to salient social cues vary with oxytocin receptor genotype in youth.在青少年中，杏仁核对显著社会线索的反应因催产素受体基因型而异。

Neuropsychologia. 2015 Dec;79(Pt A):1-9. doi: 10.1016/j.neuropsychologia.2015.10.015. Epub 2015 Oct 23.

Variant in oxytocin receptor gene is associated with amygdala volume.催产素受体基因变异与杏仁核体积有关。

Psychoneuroendocrinology. 2011 Jul;36(6):891-7. doi: 10.1016/j.psyneuen.2010.12.004. Epub 2011 Jan 3.

Oxytocin receptor gene polymorphism (rs2254298) interacts with familial risk for psychopathology to predict symptoms of depression and anxiety in adolescent girls.催产素受体基因多态性（rs2254298）与精神病理学的家族风险相互作用，预测青春期女孩抑郁和焦虑症状。

Psychoneuroendocrinology. 2011 Jan;36(1):144-7. doi: 10.1016/j.psyneuen.2010.07.003. Epub 2010 Aug 14.

Oxytocin receptor gene polymorphisms exert a modulating effect on the onset age in patients with obsessive-compulsive disorder.催产素受体基因多态性对强迫症患者发病年龄有调节作用。

Psychoneuroendocrinology. 2017 Dec;86:45-52. doi: 10.1016/j.psyneuen.2017.09.011. Epub 2017 Sep 7.

DNA methylation of OXTR is associated with parasympathetic nervous system activity and amygdala morphology.OXTR 的 DNA 甲基化与副交感神经系统活动和杏仁核形态有关。

Soc Cogn Affect Neurosci. 2018 Nov 8;13(11):1155-1162. doi: 10.1093/scan/nsy086.

Polymorphisms in the oxytocin receptor gene are associated with the development of psychopathy.催产素受体基因的多态性与精神变态的发展有关。

Dev Psychopathol. 2014 Feb;26(1):21-31. doi: 10.1017/S0954579413000485. Epub 2013 Sep 23.

The association of single-nucleotide polymorphisms in the oxytocin receptor and G protein-coupled receptor kinase 6 (GRK6) genes with oxytocin dosing requirements and labor outcomes.催产素受体和G蛋白偶联受体激酶6（GRK6）基因中的单核苷酸多态性与催产素给药需求及分娩结局的关联。

Am J Obstet Gynecol. 2017 Sep;217(3):367.e1-367.e9. doi: 10.1016/j.ajog.2017.05.023. Epub 2017 May 17.

Birth weight interacts with a functional variant of the oxytocin receptor gene (OXTR) to predict executive functioning in children.出生体重与催产素受体基因（OXTR）的一个功能性变体相互作用，可预测儿童的执行功能。

Dev Psychopathol. 2018 Feb;30(1):203-211. doi: 10.1017/S0954579417000578. Epub 2017 May 17.

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Peripheral oxytocin levels are linked to hypothalamic gray matter volume in autistic adults: a cross-sectional secondary data analysis.外周催产素水平与自闭症成人的下丘脑灰质体积有关：横断面二次数据分析。

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Genetic and epigenetic effects on couple adjustment in context of romantic relationship: A scoping systematic review.浪漫关系背景下基因和表观遗传对伴侣调适的影响：一项范围综述

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Genetic Variations in Elements of the Oxytocinergic Pathway are Associated with Attention/Hyperactivity Problems and Anxiety Problems in Childhood.催产素能通路相关基因多态性与儿童注意/多动问题及焦虑问题的相关性研究

Child Psychiatry Hum Dev. 2024 Apr;55(2):552-563. doi: 10.1007/s10578-022-01419-3. Epub 2022 Sep 10.

Gene-Environment Interactions in Face Categorization: Oxytocin Receptor Genotype x Childcare Experience Shortens Reaction Time.面部分类中的基因-环境相互作用：催产素受体基因型×儿童保育经历可缩短反应时间。

Front Psychol. 2022 Jun 9;13:873676. doi: 10.3389/fpsyg.2022.873676. eCollection 2022.

The Interaction Effect of Parental Rejection and Oxytocin Receptor Gene Polymorphism on Depression: A Cross-Cultural Study in Non-Clinical Samples.父母拒绝与催产素受体基因多态性对抑郁的交互作用：非临床样本的跨文化研究。

Int J Environ Res Public Health. 2022 May 4;19(9):5566. doi: 10.3390/ijerph19095566.

Genetics of structural and functional brain changes in autism spectrum disorder.自闭症谱系障碍中结构性和功能性大脑变化的遗传学。

Transl Psychiatry. 2020 Jul 13;10(1):229. doi: 10.1038/s41398-020-00921-3.

Morphofunctional Alterations of the Hypothalamus and Social Behavior in Autism Spectrum Disorders.自闭症谱系障碍中下丘脑的形态功能改变与社会行为

Brain Sci. 2020 Jul 8;10(7):435. doi: 10.3390/brainsci10070435.

The oxytocin receptor gene predicts brain activity during an emotion recognition task in autism.催产素受体基因预测自闭症患者在情绪识别任务中的大脑活动。

Mol Autism. 2019 Mar 12;10:12. doi: 10.1186/s13229-019-0258-4. eCollection 2019.

Structural neuroimaging correlates of social deficits are similar in autism spectrum disorder and attention-deficit/hyperactivity disorder: analysis from the POND Network.自闭症谱系障碍和注意缺陷多动障碍中社会缺陷的结构神经影像学相关性相似：来自 POND 网络的分析。

Transl Psychiatry. 2019 Feb 4;9(1):72. doi: 10.1038/s41398-019-0382-0.

Oxytocin Receptor Polymorphism Decreases Midline Neural Activations to Social Stimuli in Anorexia Nervosa.催产素受体多态性降低神经性厌食症患者对社交刺激的中线神经激活。

Front Psychol. 2018 Nov 13;9:2183. doi: 10.3389/fpsyg.2018.02183. eCollection 2018.

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Neurogenetic effects of OXTR rs2254298 in the extended limbic system of healthy Caucasian adults.

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